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- Title
The precision of remote context memories does not require the hippocampus.
- Authors
Szu-Han Wang; Teixeira, Cátia M.; Wheeler, Anne L.; Frankland, Paul W.
- Abstract
Although the clarity of many memories fades with time, some memories may maintain their original precision. Here we used a context discrimination procedure to evaluate whether the hippocampus is important in maintaining precision as memories mature. Spared discrimination in hippocampal-lesioned mice indicated that precise, remote context memories may be supported by extra-hippocampal brain regions.
- Subjects
MEMORY; INTELLECT; THOUGHT &; thinking; HIPPOCAMPUS (Brain); CEREBRAL cortex
- Publication
Nature Neuroscience, 2009, Vol 12, Issue 3, p253
- ISSN
1097-6256
- Publication type
Article
- DOI
10.1038/nn.2263