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Sodium-glucose co-transporter 2 inhibitor empagliflozin inhibits the cardiac Na+/H+ exchanger 1: persistent inhibition under various experimental conditions.
Published in:
Cardiovascular Research, 2021, v. 117, n. 14, p. 2699, doi. 10.1093/cvr/cvab129
By:
- Zuurbier, Coert J;
- Baartscheer, Antonius;
- Schumacher, Cees A;
- Fiolet, Jan W T;
- Coronel, Ruben
Publication type:
Article
Delayed ischaemic contracture onset by empagliflozin associates with NHE1 inhibition and is dependent on insulin in isolated mouse hearts.
Published in:
Cardiovascular Research, 2019, v. 115, n. 10, p. 1533, doi. 10.1093/cvr/cvz004
By:
- Uthman, Laween;
- Nederlof, Rianne;
- Eerbeek, Otto;
- Baartscheer, Antonius;
- Schumacher, Cees;
- Buchholtz, Ninée;
- Hollmann, Markus W;
- Coronel, Ruben;
- Weber, Nina C;
- Zuurbier, Coert J
Publication type:
Article
Role of Ca2+-activated Cl- current in ventricular action potentials of sheep during adrenoceptor stimulation.
Published in:
Experimental Physiology, 2001, v. 86, n. 2, p. 151, doi. 10.1113/eph8602113
By:
- Verkerk, Arie O.;
- Schumacher, Cees A.;
- Ginneken, Antoni C. G. van;
- Veldkamp, Marieke W.;
- Ravesloot, Jan H.
Publication type:
Article
Protease XIV abolishes NHE inhibition by empagliflozin in cardiac cells.
Published in:
Frontiers in Physiology, 2023, p. 01, doi. 10.3389/fphys.2023.1179131
By:
- Sha Chen;
- Schumacher, Cees A.;
- Van Amersfoorth, Shirley C. M.;
- Fiolet, Jan W. T.;
- Baartscheer, Antonius;
- Veldkamp, Marieke W.;
- Coronel, Ruben;
- Zuurbier, Coert J.
Publication type:
Article
Ventricular fibrillation hampers the restoration of creatine-phosphate levels during simulated cardiopulmonary resuscitations.
Published in:
EP: Europace, 2012, v. 14, n. 10, p. 1518, doi. 10.1093/europace/eus078
By:
- Hoogendijk, Mark G.;
- Schumacher, Cees A.;
- Belterman, Charly N.W.;
- Boukens, Bas J.;
- Berdowski, Jocelyn;
- de Bakker, Jacques M.T.;
- Koster, Rudolph W.;
- Coronel, Ruben
Publication type:
Article
Direct Cardiac Actions of Sodium Glucose Cotransporter 2 Inhibitors Target Pathogenic Mechanisms Underlying Heart Failure in Diabetic Patients.
Published in:
Frontiers in Physiology, 2018, p. N.PAG, doi. 10.3389/fphys.2018.01575
By:
- Uthman, Laween;
- Baartscheer, Antonius;
- Schumacher, Cees A.;
- Fiolet, Jan W. T.;
- Kuschma, Marius C.;
- Hollmann, Markus W.;
- Coronel, Ruben;
- Weber, Nina C.;
- Zuurbier, Coert J.
Publication type:
Article
Reducing mitochondrial bound hexokinase II mediates transition from non-injurious into injurious ischemia/reperfusion of the intact heart.
Published in:
Journal of Physiology & Biochemistry, 2016, v. 73, n. 3, p. 323, doi. 10.1007/s13105-017-0555-3
By:
- Nederlof, Rianne;
- Gürel-Gurevin, Ebru;
- Eerbeek, Otto;
- Xie, Chaoqin;
- Deijs, G. Sjoerd;
- Konkel, Moritz;
- Hu, Jun;
- Weber, Nina;
- Schumacher, Cees;
- Baartscheer, Antonius;
- Mik, Egbert;
- Hollmann, Markus;
- Akar, Fadi;
- Zuurbier, Coert
Publication type:
Article
In vivo mouse myocardial 31P MRS using three-dimensional image-selected in vivo spectroscopy (3D ISIS): technical considerations and biochemical validations.
Published in:
NMR in Biomedicine, 2015, v. 28, n. 10, p. 1218, doi. 10.1002/nbm.3371
By:
- Bakermans, Adrianus J.;
- Abdurrachim, Desiree;
- Nierop, Bastiaan J.;
- Koeman, Anneke;
- Kroon, Inge;
- Baartscheer, Antonius;
- Schumacher, Cees A.;
- Strijkers, Gustav J.;
- Houten, Sander M.;
- Zuurbier, Coert J.;
- Nicolay, Klaas;
- Prompers, Jeanine J.
Publication type:
Article
Class effects of SGLT2 inhibitors in mouse cardiomyocytes and hearts: inhibition of Na+/H+ exchanger, lowering of cytosolic Na+ and vasodilation.
Published in:
Diabetologia, 2018, v. 61, n. 3, p. 722, doi. 10.1007/s00125-017-4509-7
By:
- Uthman, Laween;
- Baartscheer, Antonius;
- Bleijlevens, Boris;
- Schumacher, Cees A.;
- Fiolet, Jan W. T.;
- Koeman, Anneke;
- Jancev, Milena;
- Hollmann, Markus W.;
- Weber, Nina C.;
- Coronel, Ruben;
- Zuurbier, Coert J.
Publication type:
Article
Empagliflozin decreases myocardial cytoplasmic Na through inhibition of the cardiac Na/H exchanger in rats and rabbits.
Published in:
Diabetologia, 2017, v. 60, n. 3, p. 568, doi. 10.1007/s00125-016-4134-x
By:
- Baartscheer, Antonius;
- Schumacher, Cees;
- Wüst, Rob;
- Fiolet, Jan;
- Stienen, Ger;
- Coronel, Ruben;
- Zuurbier, Coert
Publication type:
Article
Dietary n-3 fatty acids promote arrhythmias during acute regional myocardial ischemia in isolated pig hearts
Published in:
Cardiovascular Research, 2007, v. 73, n. 2, p. 386, doi. 10.1016/j.cardiores.2006.10.006
By:
- Coronel, Ruben;
- Wilms-Schopman, Francien J.G.;
- Den Ruijter, Hester M.;
- Belterman, Charly N.;
- Schumacher, Cees A.;
- Opthof, Tobias;
- Hovenier, Robert;
- Lemmens, Arnoldina G.;
- Terpstra, Antonius H.M.;
- Katan, Martijn B.;
- Zock, Peter
Publication type:
Article
Incorporated sarcolemmal fish oil fatty acids shorten pig ventricular action potentials
Published in:
Cardiovascular Research, 2006, v. 70, n. 3, p. 509, doi. 10.1016/j.cardiores.2006.02.022
By:
- Verkerk, Arie O.;
- van Ginneken, Antoni C.G.;
- Berecki, Géza;
- den Ruijter, Hester M.;
- Schumacher, Cees A.;
- Veldkamp, Marieke W.;
- Baartscheer, Antonius;
- Casini, Simona;
- Opthof, Tobias;
- Hovenier, Robert;
- Fiolet, Jan W.T.;
- Zock, Peter L.;
- Coronel, Ruben
Publication type:
Article
Chronic inhibition of Na+/H+-exchanger attenuates cardiac hypertrophy and prevents cellular remodeling in heart failure
Published in:
Cardiovascular Research, 2005, v. 65, n. 1, p. 83, doi. 10.1016/j.cardiores.2004.09.024
By:
- Baartscheer, Antonius;
- Schumacher, Cees A.;
- van Borren, Marcel M.G.J.;
- Belterman, Charly N.W.;
- Coronel, Ruben;
- Opthof, Tobias;
- Fiolet, Jan W.T.
Publication type:
Article
Intrinsic heterogeneity in repolarization is increased in isolated failing rabbit cardiomyocytes during simulated ischemia
Published in:
Cardiovascular Research, 2003, v. 59, n. 3, p. 705, doi. 10.1016/S0008-6363(03)00460-7
By:
- de Groot, Joris R.;
- Schumacher, Cees A.;
- Verkerk, Arie O.;
- Baartscheer, Antonius;
- Fiolet, Jan W.T.;
- Coronel, Ruben
Publication type:
Article
SR calcium handling and calcium after-transients in a rabbit model of heart failure
Published in:
Cardiovascular Research, 2003, v. 58, n. 1, p. 99, doi. 10.1016/S0008-6363(02)00854-4
By:
- Baartscheer, Antonius;
- Schumacher, Cees A.;
- Belterman, Charly N.W.;
- Coronel, Ruben;
- Fiolet, Jan W.T.
Publication type:
Article
Neurokinin-3 receptor activation selectively prolongs atrial refractoriness by inhibition of a background K+ channel.
Published in:
Nature Communications, 2018, v. 9, p. 1, doi. 10.1038/s41467-018-06530-5
By:
- Veldkamp, Marieke W.;
- Geuzebroek, Guillaume S. C.;
- Baartscheer, Antonius;
- Verkerk, Arie O.;
- Schumacher, Cees A.;
- Suarez, Gedeon G.;
- Berger, Wouter R.;
- Casini, Simona;
- van Amersfoorth, Shirley C. M.;
- Scholman, Koen T.;
- Driessen, Antoine H. G.;
- Belterman, Charly N. W.;
- van Ginneken, Antoni C. G.;
- de Groot, Joris R.;
- de Bakker, Jacques M. T.;
- Remme, Carol Ann;
- Boukens, Bas J.;
- Coronel, Ruben
Publication type:
Article

Found: 16

Sodium-glucose co-transporter 2 inhibitor empagliflozin inhibits the cardiac Na+/H+ exchanger 1: persistent inhibition under various experimental conditions.

Delayed ischaemic contracture onset by empagliflozin associates with NHE1 inhibition and is dependent on insulin in isolated mouse hearts.

Role of Ca2+-activated Cl- current in ventricular action potentials of sheep during adrenoceptor stimulation.

Protease XIV abolishes NHE inhibition by empagliflozin in cardiac cells.

Ventricular fibrillation hampers the restoration of creatine-phosphate levels during simulated cardiopulmonary resuscitations.

Direct Cardiac Actions of Sodium Glucose Cotransporter 2 Inhibitors Target Pathogenic Mechanisms Underlying Heart Failure in Diabetic Patients.

Reducing mitochondrial bound hexokinase II mediates transition from non-injurious into injurious ischemia/reperfusion of the intact heart.

In vivo mouse myocardial <sup>31</sup>P MRS using three-dimensional image-selected in vivo spectroscopy (3D ISIS): technical considerations and biochemical validations.

Class effects of SGLT2 inhibitors in mouse cardiomyocytes and hearts: inhibition of Na<sup>+</sup>/H<sup>+</sup> exchanger, lowering of cytosolic Na<sup>+</sup> and vasodilation.

Empagliflozin decreases myocardial cytoplasmic Na through inhibition of the cardiac Na/H exchanger in rats and rabbits.

Dietary n-3 fatty acids promote arrhythmias during acute regional myocardial ischemia in isolated pig hearts

Incorporated sarcolemmal fish oil fatty acids shorten pig ventricular action potentials

Chronic inhibition of Na<sup>+</sup>/H<sup>+</sup>-exchanger attenuates cardiac hypertrophy and prevents cellular remodeling in heart failure

Intrinsic heterogeneity in repolarization is increased in isolated failing rabbit cardiomyocytes during simulated ischemia

SR calcium handling and calcium after-transients in a rabbit model of heart failure

Neurokinin-3 receptor activation selectively prolongs atrial refractoriness by inhibition of a background K<sup>+</sup> channel.