We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
HEPATOPROTECTIVE ACTIVITY OF ALCOHOLIC EXTRACTS OF BOERHAAVIA DIFFUSA AND ANISOCHLILUS CARNOSUS AGAINST CARBON TETRACHLORIDE INDUCED HEPATOTOXICITY IN RATS.
- Authors
Venkatesh, P.; Dinakar, A.; Senthilkumar, N.
- Abstract
An alcoholic extract of stem and leaves of Boerhaavia Diffusa (AEBD) and leaves of Anisochilus Carnosus (AEAC) was studied for hepatoprotective activity against Carbon Tetrachloride (CCl4) induced hepatotoxicity in rats. Hepatotoxicity was introduced in Albino rats of either sex by intraperitoneal injection of CCl4 (in olive oil). Alcoholic extracts of AEBD and AEAC were administered to the experimental rats at the dose levels 150mg and 300mg/kg body weight, 200mg and 400mg/kg body weight of AEBD and AEAC respectively. The hepatoprotective effects of the extracts were evaluated by the assay of liver function biochemical parameters like Serum Glutamate Oxaloacetate Transaminase (SGOT), Serum Glutamate Pyruvate Tranaminase (SGPT), Serum Alkaline Phosphatase (SALP), Total and Direct Serum Bilirubin. It was concluded that, the alcoholic extracts of AEBD and AEAC possess hepatoprotective activity against CCl4 induced hepatotoxicity in rats.
- Subjects
PLANT extracts; BOERHAVIA; CARBON tetrachloride; TOXICITY testing; LABORATORY animals; THERAPEUTICS
- Publication
International Journal of Pharmacology & Biological Sciences, 2012, Vol 6, Issue 3, p11
- ISSN
0973-6808
- Publication type
Article