We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Safety and Efficacy of a Novel Antiaging Skin Care Regimen Containing Neutraceuticals and Growth Factors on the Facial Skin of Women: A 12-Week Open-label Study.
- Authors
SADOWSKI, GEORGE; SADOWSKI, JULIAN
- Abstract
BACKGROUND: Due to both intrinsic and extrinsic damage, the skin is where easily noticable signs of aging manifest. OBJECTIVE: We sought to assess the effects of two complex novel topical formulations, L'Unique Miracular Facial Serum (LMFS) and L'Unique Skin Essence (LSE) (Nourishing Biologicals LLC, St. Augustine, Florida) on hydration, firmness, elasticity, wrinkling, and pore size of facial skin after initial application and then after four, eight, and 12 weeks of use. METHODS: An open-label study was conducted on subjects (N=32) between the ages of 45 and 65 years (mean: 57 years). Subjects were treated with a twice-daily application of LMFS and LSE for a total of 12 weeks following a one-week washout period. The test products were gently applied in a circular motion to the face each morning and evening. Measurements of skin hydration, transepidermal water loss (TEWL), and skin elasticity and firmness and three-dimensional skin surface evaluations were performed at each visit. Skin lift and pore size assessments were also completed using clinical photography. Subjective outcomes were assessed by a posttreatment product efficiency survey at the end of each visit. RESULTS: Objective instrumental measurements showed statistically significant improvements in skin hydration (20.19%), TEWL (25.96% at 15 minutes), firmness (24.77%), skin elasticity (11.40%), and skin lift (5.41%) with product use. Improvements in pore size and wrinkle depth were not statistically significant. CONCLUSION: Use of the test products produced significant improvements in skin hydration, TEWL, firmness, and skin elasticity with associated improvements in facial skin appearance.
- Subjects
SAINT Augustine (Fla.); FLORIDA; SKIN care; GROWTH factors; FUNCTIONAL foods; SKIN; CIRCULAR motion
- Publication
Journal of Clinical & Aesthetic Dermatology, 2020, Vol 13, Issue 6, p24
- ISSN
1941-2789
- Publication type
journal article