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- Title
Comparison of antifungal activity of different extracts from Satureja khuzistanica Jamzad against dermatophytes.
- Authors
MAHBOUBI, Mohaddese; KAZEMPOUR, Nastaran
- Abstract
Dermatophytosis, commonly known as ringworms can cause superficial infections in the skin, hair and nails. Due to the ability of dermatophytes to acquire the resistance to available antifungal agents and their human toxicities, we compared the antifungal activity of different extracts of Satureja khuzistanica (essential oil, ethanol and aqueous extracts) against dermatophyte fungi by disc diffusion and micro broth dilution assays. The antifungal activity of S. khuzistanica essential oil (MIC =40-190 μg/ml) was higher than its ethanol extract (MIC =40-770 μg/ml); while S. khuzistanica aqueous extract had no antifungal activity against dermatophytes (MIC=1550->3100 μg/ml). Their anti-elastase activity evaluations confirmed that S. khuzistanica aqueous and ethanol extracts had the higher anti-elastase activity than that of essential oil. S. khuzistanica essential oil or its ethanol extract can be further extended to explore more for their antifungal activities.
- Subjects
RINGWORM; SKIN infections; DERMATOPHYTES
- Publication
Biharean Biologist, 2015, Vol 9, Issue 2, p105
- ISSN
1843-5637
- Publication type
Article