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- Title
The use of a urinary estrone conjugates assay for detection of optimal mating time in the cynomolgus macaque (Macaca fascicularis).
- Authors
Behboodi, Esmail; Katz, David F.; Samuels, Steven J.; Tell, Lisa; Hendrickx, Andrew G.; Lasley, Bill L.
- Abstract
Forty‐four female cynomolgus macaques (Macaca fascicularis) were examined to determine the optimum fertile period for mating. Daily urinary estrone conjugates (E1C) were measured, beginning on day 7 of the menstrual cycle, until a 1.5‐gold E1C rise above the baseline was detected. The females were bred the next morning. Pregnancies were verified in all animals at day 18 postbreeding, and/or on day 25 postbreeding. Serum progesterone levels were used to correlate the relationship between ovulation and the E1C peak. Forty‐four of the 57 cycles indicated a urinary E1C peak between days 10–15 of the menstrual cycle; this peak occurred on the day following the initial 1.5‐fold to twofold rise in 90% of the cycles. A single 2‐hr mating period the day before, the day of, or the day after the E1C peak resulted in conception in 17 of 44 (38.6%) animals.
- Publication
Journal of Medical Primatology, 1991, Vol 20, Issue 5, p229
- ISSN
0047-2565
- Publication type
Article
- DOI
10.1111/j.1600-0684.1991.tb00525.x