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- Title
Die renale Denervation als neue Behandlungsmöglichkeit der therapierefraktären arteriellen Hypertonie.
- Authors
Himmel, F.; Bode, F.; Schunkert, H.; Weil, J.
- Abstract
Resistant hypertension is defined as blood pressure that remains above therapeutic goal despite the use of 3 antihypertensive drugs including a diuretic. After exclusion of secondary causes and medical incompliance, the estimated prevalence of resistant arterial hypertension ranges from 4% to 19% in hypertensive patients. Treatment requires a multimodal therapeutic approach. Hyperactivation of the sympathetic nervous system plays a key role in the genesis of hypertension. Targeting renal sympathetic nerves, percutaneous catheter-based renal denervation is a new therapeutic option for the treatment of resistant arterial hypertension in selected drug resistant patients.
- Subjects
HYPERTENSION; THERAPEUTICS; BLOOD pressure; ANTIHYPERTENSIVE agents; DISEASE prevalence; SYMPATHETIC nervous system; DRUG resistance; DENERVATION
- Publication
Praxis (16618157), 2011, Vol 100, Issue 22, p1353
- ISSN
1661-8157
- Publication type
Article
- DOI
10.1024/1661-8157/a000713