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- Title
Innovations in the Management of Vaginal Cancer.
- Authors
Kulkarni, Anjali; Dogra, Nupur; Zigras, Tiffany
- Abstract
Primary vaginal cancer is a rare gynecologic malignancy. Given the rarity of the disease, standardized approaches to management are limited, and a great variety of therapeutic conditions are endorsed. This paper reviews advances in surgical approaches, radiation, chemoradiation, and immunotherapy. Advances in surgical management including the increasing use of laparoscopic and endoscopic approaches, as well as the novel techniques in vaginal reconstruction, are reviewed. Concurrent chemoradiation remains a mainstay of treatment for vaginal cancer and has improved local control of disease and overall survival. Additionally, with metastatic disease or situations where toxicity from CCRT is unacceptable, systemic therapies including immunotherapy approaches are reviewed.
- Subjects
VAGINAL tumors; RADIATION; IMMUNOTHERAPY; OVERALL survival; METASTASIS
- Publication
Current Oncology, 2022, Vol 29, Issue 5, p3082
- ISSN
1198-0052
- Publication type
Article
- DOI
10.3390/curroncol29050250