OpenURL Connection Search

Select item for more details and to access through your institution.

Development of New Potential Inhibitors of β1 Integrins through In Silico Methods—Screening and Computational Validation.
Published in:
Life (2075-1729), 2022, v. 12, n. 7, p. 932, doi. 10.3390/life12070932
By:
- Vasconcelos, Disraeli;
- Chaves, Beatriz;
- Albuquerque, Aline;
- Andrade, Luca;
- Henriques, Andrielly;
- Sartori, Geraldo;
- Savino, Wilson;
- Caffarena, Ernesto;
- Martins-Da-Silva, João Herminio
Publication type:
Article
Caracterização do envelhecimento populacional no município do Rio de Janeiro: contribuições para políticas públicas sustentáveis.
Published in:
Cadernos Saúde Coletiva, 2016, v. 24, n. 1, p. 63, doi. 10.1590/1414-462X201600010272
By:
- da Silveira Barroso Alves, Davi;
- Serrano Barbosa, Maria Tereza;
- Raúl Caffarena, Ernesto;
- da Silva, Alexandre Sousa
Publication type:
Article
Using RNA Sequence and Structure for the Prediction of Riboswitch Aptamer: A Comprehensive Review of Available Software and Tools.
Published in:
Frontiers in Genetics, 2018, p. 1, doi. 10.3389/fgene.2017.00231
By:
- Antunes, Deborah;
- Jorge, Natasha A. N.;
- Caffarena, Ernesto R.;
- Passetti, Fabio
Publication type:
Article
Dynamic identification of H2 epitopes from Leishmania (Leishmania) amazonensis cysteine proteinase B with potential immune activity during murine infection.
Published in:
Journal of Molecular Recognition, 2014, v. 27, n. 2, p. 98, doi. 10.1002/jmr.2334
By:
- Souza‐Silva, Franklin;
- Pereira, Bernardo A. S.;
- Finkelstein, Léa C.;
- Zucolotto, Valtencir;
- Caffarena, Ernesto R.;
- Alves, Carlos R.
Publication type:
Article
Insights into the Mechanism of Ethionamide Resistance in Mycobacterium tuberculosis through an in silico Structural Evaluation of EthA and Mutants Identified in Clinical Isolates.
Published in:
Catalysts (2073-4344), 2020, v. 10, n. 5, p. 543, doi. 10.3390/catal10050543
By:
- de Souza, Vinicius Carius;
- Antunes, Deborah;
- Santos, Lucianna H.S.;
- Goliatt, Priscila Vanessa Zabala Capriles;
- Caffarena, Ernesto Raul;
- Guimarães, Ana Carolina Ramos;
- Galvão, Teca Calcagno
Publication type:
Article
Mycobacterium tuberculosis and M. bovis BCG Moreau Fumarate Reductase Operons Produce Different Polypeptides That May Be Related to Non-canonical Functions.
Published in:
Frontiers in Microbiology, 2021, v. 11, p. N.PAG, doi. 10.3389/fmicb.2020.624121
By:
- Schwarz, Marcos Gustavo Araujo;
- Antunes, Deborah;
- Corrêa, Paloma Rezende;
- Silva-Gonçalves, Antônio José da;
- Malaga, Wladimir;
- Caffarena, Ernesto Raul;
- Guilhot, Christophe;
- Mendonça-Lima, Leila
Publication type:
Article
Effects of the Q80K Polymorphism on the Physicochemical Properties of Hepatitis C Virus Subtype 1a NS3 Protease.
Published in:
Viruses (1999-4915), 2019, v. 11, n. 8, p. 691, doi. 10.3390/v11080691
By:
- Peres-da-Silva, Allan;
- Antunes, Deborah;
- Quintanilha Torres, André Luiz;
- Caffarena, Ernesto Raul;
- Lampe, Elisabeth
Publication type:
Article
Toll-like Receptor 1 N248S Single-Nucleotide Polymorphism Is Associated With Leprosy Risk and Regulates Immune Activation During Mycobacterial Infection.
Published in:
2013
By:
- de Sales Marques, Carolinne;
- Brito-de-Souza, Vânia N;
- Guerreiro, Luana Tatiana Albuquerque;
- Martins, Joao H;
- Amaral, Evaldo P;
- Cardoso, Cynthia C;
- Dias-Batista, Ida Maria Foschiani;
- da Silva, Weber Laurentino;
- Nery, José Augusto C;
- Medeiros, Priscila;
- Gigliotti, Patricia;
- Campanelli, Ana Paula;
- Virmond, Marcos;
- Sarno, Euzenir Nunes;
- Mira, Marcelo T;
- Lana, Francisco C F;
- Caffarena, Ernesto Raúl;
- Pacheco, Antonio G;
- Pereira, Ana Carla;
- Moraes, Milton Ozório
Publication type:
Journal Article
Toll-like Receptor 1 N248S Single-Nucleotide Polymorphism Is Associated With Leprosy Risk and Regulates Immune Activation During Mycobacterial Infection.
Published in:
Journal of Infectious Diseases, 2013, v. 208, n. 1, p. 120, doi. 10.1093/infdis/jit133
By:
- de Sales Marques, Carolinne;
- Brito-de-Souza, Vânia N.;
- Guerreiro, Luana Tatiana Albuquerque;
- Martins, João H.;
- Amaral, Evaldo P.;
- Cardoso, Cynthia C.;
- Dias-Batista, Ida Maria Foschiani;
- da Silva, Weber Laurentino;
- Nery, José Augusto C.;
- Medeiros, Priscila;
- Gigliotti, Patricia;
- Campanelli, Ana Paula;
- Virmond, Marcos;
- Sarno, Euzenir Nunes;
- Mira, Marcelo T.;
- Lana, Francisco C. F.;
- Caffarena, Ernesto Raúl;
- Pacheco, Antonio G.;
- Pereira, Ana Carla;
- Moraes, Milton Ozório
Publication type:
Article
Unraveling RNA dynamical behavior of TPP riboswitches: a comparison between Escherichia coli and Arabidopsis thaliana.
Published in:
Scientific Reports, 2019, v. 9, n. 1, p. 1, doi. 10.1038/s41598-019-40875-1
By:
- Antunes, Deborah;
- Jorge, Natasha Andressa Nogueira;
- Garcia de Souza Costa, Mauricio;
- Passetti, Fabio;
- Caffarena, Ernesto Raul
Publication type:
Article
Studies of molecular docking between fibroblast growth factor and heparin using generalized simulated annealing.
Published in:
International Journal of Quantum Chemistry, 2008, v. 108, n. 13, p. 2608, doi. 10.1002/qua.21731
By:
- da Rocha Pita, Samuel Silva;
- Fernandes, Tácio Vinício Amorim;
- Caffarena, Ernesto Raul;
- Pascutti, Pedro Geraldo
Publication type:
Article
In silico analysis of the V66M variant of human BDNF in psychiatric disorders: An approach to precision medicine.
Published in:
PLoS ONE, 2019, v. 14, n. 4, p. 1, doi. 10.1371/journal.pone.0215508
By:
- De Oliveira, Clara Carolina Silva;
- Pereira, Gabriel Rodrigues Coutinho;
- De Alcantara, Jamile Yvis Santos;
- Antunes, Deborah;
- Caffarena, Ernesto Raul;
- De Mesquita, Joelma Freire
Publication type:
Article
Thermostabilizing mechanisms of canonical single amino acid substitutions at a GH1 β‐glucosidase probed by multiple MD and computational approaches.
Published in:
Proteins, 2023, v. 91, n. 2, p. 218, doi. 10.1002/prot.26424
By:
- Rocha, Rafael Eduardo Oliveira;
- Mariano, Diego César Batista;
- Almeida, Tiago Silva;
- CorrêaCosta, Leon Sulfierry;
- Fischer, Pedro Henrique Camargo;
- Santos, Lucianna Helene;
- Caffarena, Ernesto Raul;
- da Silveira, Carlos Henrique;
- Lamp, Leonida M.;
- Fernandez‐Quintero, Monica Lisa;
- Liedl, Klaus Roman;
- de Melo‐Minardi, Raquel Cardoso;
- de Lima, Leonardo Henrique França
Publication type:
Article
Essential dynamics of the cold denaturation: pressure and temperature effects in yeast frataxin.
Published in:
Proteins, 2017, v. 85, n. 1, p. 125, doi. 10.1002/prot.25205
By:
- Espinosa, Yanis R.;
- Grigera, J. Raúl;
- Caffarena, Ernesto R.
Publication type:
Article
Exploring the unbinding of Leishmania (L.) amazonensis CPB derived-epitopes from H2 MHC class I proteins.
Published in:
Proteins, 2016, v. 84, n. 4, p. 473, doi. 10.1002/prot.24994
By:
- Brandt, Artur M. L.;
- Batista, Paulo Ricardo;
- Souza‐Silva, Franklin;
- Alves, Carlos Roberto;
- Caffarena, Ernesto Raul
Publication type:
Article
Computational modeling of the bHLH domain of the transcription factor TWIST1 and R118C, S144R and K145E mutants.
Published in:
BMC Bioinformatics, 2012, v. 13, n. 1, p. 184, doi. 10.1186/1471-2105-13-184
By:
- Maia, Amanda M.;
- da Silva, João HM;
- Mencalha, André L.;
- Caffarena, Ernesto R.;
- Abdelhay, Eliana
Publication type:
Article
Molecular interactions of c-ABL mutants in complex with imatinib/nilotinib: a computational study using linear interaction energy (LIE) calculations.
Published in:
Journal of Molecular Modeling, 2012, v. 18, n. 9, p. 4333, doi. 10.1007/s00894-012-1436-x
By:
- Pereira, Elen;
- Moreira, Miguel;
- Caffarena, Ernesto
Publication type:
Article
Structure-based functional inference of hypothetical proteins from Mycoplasma hyopneumoniae.
Published in:
Journal of Molecular Modeling, 2012, v. 18, n. 5, p. 1917, doi. 10.1007/s00894-011-1212-3
By:
- Fonsêca, Marbella;
- Zaha, Arnaldo;
- Caffarena, Ernesto;
- Vasconcelos, Ana
Publication type:
Article
Naturally Occurring Genetic Variants of Human Caspase-1 Differ Considerably in Structure and the Ability to Activate Interleukin-1β.
Published in:
Human Mutation, 2013, v. 34, n. 1, p. 122, doi. 10.1002/humu.22169
By:
- Luksch, Hella;
- Romanowski, Michael J.;
- Chara, Osvaldo;
- Tüngler, Victoria;
- Caffarena, Ernesto R.;
- Heymann, Michael C.;
- Lohse, Peter;
- Aksentijevich, Ivona;
- Remmers, Elaine F.;
- Flecks, Silvana;
- Quoos, Nadine;
- Gramatté, Johannes;
- Petzold, Cathleen;
- Hofmann, Sigrun R.;
- Winkler, Stefan;
- Pessler, Frank;
- Kallinich, Tilmann;
- Ganser, Gerd;
- Nimtz‐Talaska, Antje;
- Baumann, Ulrich
Publication type:
Article
Identification of Novel and Recurrent RMRP Variants in a Series of Brazilian Patients with Cartilage-Hair Hypoplasia: McKusick Syndrome.
Published in:
Molecular Syndromology, 2019, v. 10, n. 5, p. 255, doi. 10.1159/000501892
By:
- Gomes, Maria E.;
- Calatrava Paternostro, Luiza;
- Moura, Valéria R.;
- antunes, Deborah;
- Caffarena, Ernesto R.;
- Horovitz, Dafne;
- Sanseverino, Maria T.;
- Ferraz Leal, Gabriela;
- Felix, Têmis M.;
- Pontes Cavalcanti, Denise;
- Clinton Llerena Jr., Juan;
- Gonzalez, Sayonara
Publication type:
Article
RASopathy Cohort of Patients Enrolled in a Brazilian Reference Center for Rare Diseases: A Novel Familial LZTR1 Variant and Recurrent Mutations.
Published in:
Application of Clinical Genetics, 2022, v. 15, p. 153, doi. 10.2147/TACG.S372761
By:
- Rabelo, Natana Chaves;
- Gomes, Maria Eduarda;
- de Oliveira Moraes, Isabelle;
- Pfisterer, Juliana Cantagalli;
- de Morais, Guilherme Loss;
- Antunes, Deborah;
- Caffarena, Ernesto Raúl;
- Jr, Juan Llerena;
- Gonzalez, Sayonara
Publication type:
Article
New parameterization approaches of the LIE method to improve free energy calculations of PlmII-Inhibitors complexes.
Published in:
Journal of Computational Chemistry, 2010, v. 31, n. 15, p. 2723, doi. 10.1002/jcc.21566
By:
- VALIENTE, PEDRO A.;
- L., ALEJANDRO GIL;
- BATISTA, PAULO R.;
- CAFFARENA, ERNESTO R.;
- PONS, TIRSO;
- PASCUTTI, PEDRO G.
Publication type:
Article
Structural and Molecular Modeling Features of P2X Receptors.
Published in:
International Journal of Molecular Sciences, 2014, v. 15, n. 3, p. 4531, doi. 10.3390/ijms15034531
By:
- Alves, Luiz Anastacio;
- da Silva, João Herminio Martins;
- Moreira Ferreira, Dinarte Neto;
- Fidalgo-Neto, Antonio Augusto;
- Nogueira Teixeira, Pedro Celso;
- de Souza, Cristina Alves Magalhães;
- Caffarena, Ernesto Raúl;
- de Freitas, Mônica Santos
Publication type:
Article
Structural Characterization of Heat Shock Protein 90β and Molecular Interactions with Geldanamycin and Ritonavir: A Computational Study.
Published in:
International Journal of Molecular Sciences, 2024, v. 25, n. 16, p. 8782, doi. 10.3390/ijms25168782
By:
- Lima, Carlyle Ribeiro;
- Antunes, Deborah;
- Caffarena, Ernesto;
- Carels, Nicolas
Publication type:
Article
Differences in Charge Distribution in Leishmania tarentolae Leishmanolysin Result in a Reduced Enzymatic Activity.
Published in:
International Journal of Molecular Sciences, 2022, v. 23, n. 14, p. 7660, doi. 10.3390/ijms23147660
By:
- Ennes-Vidal, Vítor;
- Antunes, Deborah;
- Poláková, Ester;
- Yurchenko, Vyacheslav;
- Oliveira, Simone S. C.;
- Faria da Mota, Fabio;
- Guimaraes, Ana Carolina R.;
- Caffarena, Ernesto R.;
- S. Santos, André L.;
- Branquinha, Marta H.;
- d'Avila-Levy, Claudia M.
Publication type:
Article
Bacterial 2′-Deoxyguanosine Riboswitch Classes as Potential Targets for Antibiotics: A Structure and Dynamics Study.
Published in:
International Journal of Molecular Sciences, 2022, v. 23, n. 4, p. 1925, doi. 10.3390/ijms23041925
By:
- Antunes, Deborah;
- Santos, Lucianna H. S.;
- Caffarena, Ernesto Raul;
- Guimarães, Ana Carolina Ramos
Publication type:
Article

Found: 26