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- Title
On the Critique by Colin Anderson of ‘A Reply to Dembic: On an End to the Beginning of Mis-Understanding the Immune Response’.
- Authors
Cohn, M.
- Abstract
My proposal of a set of postulates that can be used to guide computer modeling has understandably met with significant criticism at two levels, semantic and conceptual. The major source of contention is my assumption that the sorting of the paratopic repertoire is both necessary and sufficient to explain the evolutionarily selected mechanism for the self-nonself discrimination. While `necessary' is agreed upon, `sufficient' is debatable as this commentary illustrates. My essay is in defense of `sufficiency'.
- Subjects
ANDERSON, Colin; IMMUNE response; COMPUTER simulation; CHARACTERISTIC functions; SEMANTICS
- Publication
Scandinavian Journal of Immunology, 2009, Vol 70, Issue 1, p1
- ISSN
0300-9475
- Publication type
Article
- DOI
10.1111/j.1365-3083.2009.02264.x