We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Expression of the CD15 antigen in hepatocellular carcinoma.
- Authors
Torii, Akihito; Nakayama, Atsuo; Harada, Akio; Nakao, Akimasa; Nonami, Toshiaki; Sakamoto, Junichi; Watanabe, Tadashi; Ito, Masafumi; Takagi, Hiroshi; Torii, A; Nakayama, A; Harada, A; Nakao, A; Nonami, T; Sakamoto, J; Watanabe, T; Ito, M; Takagi, H
- Abstract
Expression of the CD15 antigen, which is one of the adhesion molecules, was studied immunohistochemically to investigate the mechanism of intrahepatic metastasis in 56 hepatocellular carcinomas (HCC). Twenty-nine percent (16 of 56) of the HCC expressed CD15. No noncancerous hepatocytes expressed CD15. CD15-positive HCC had histologic intrahepatic metastasis more often than did CD15-negative HCC; the difference was statistically significant (P < 0.02). The survival rate of patients with CD15-negative HCC was better than that of patients with CD15-positive HCC, although the difference was not statistically significant. The authors speculate that there is a relationship between the expression of CD15 and intrahepatic metastasis in HCC.
- Publication
Cancer (0008543X), 1993, Vol 71, Issue 12, p3864
- ISSN
0008-543X
- Publication type
journal article
- DOI
10.1002/1097-0142(19930615)71:12<3864::AID-CNCR2820711212>3.0.CO;2-5