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- Title
A Historical Survey of Key Epidemiological Studies of Ionizing Radiation Exposure.
- Authors
Little, Mark P.; Bazyka, Dimitry; Gonzalez, Amy Berrington de; Brenner, Alina V.; Chumak, Vadim V.; Cullings, Harry M.; Daniels, Robert D.; French, Benjamin; Grant, Eric; Hamada, Nobuyuki; Hauptmann, Michael; Kendall, Gerald M.; Laurier, Dominique; Lee, Choonsik; Lee, Won Jin; Linet, Martha S.; Mabuchi, Kiyohiko; Morton, Lindsay M.; Muirhead, Colin R.; Preston, Dale L.
- Abstract
In this article we review the history of key epidemiological studies of populations exposed to ionizing radiation. We highlight historical and recent findings regarding radiation-associated risks for incidence and mortality of cancer and non-cancer outcomes with emphasis on study design and methods of exposure assessment and dose estimation along with brief consideration of sources of bias for a few of the more important studies. We examine the findings from the epidemiological studies of the Japanese atomic bomb survivors, persons exposed to radiation for diagnostic or therapeutic purposes, those exposed to environmental sources including Chornobyl and other reactor accidents, and occupationally exposed cohorts. We also summarize results of pooled studies. These summaries are necessarily brief, but we provide references to more detailed information. We discuss possible future directions of study, to include assessment of susceptible populations, and possible new populations, data sources, study designs and methods of analysis.
- Subjects
IONIZING radiation; NUCLEAR reactor accidents; EXPOSURE dose; ATOMIC bomb; RADIATION exposure
- Publication
Radiation Research, 2024, Vol 202, Issue 2, p432
- ISSN
0033-7587
- Publication type
Article
- DOI
10.1667/RADE-24-00021.1