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- Title
Lower bone mineral density in geriatric patients with monoclonal gammopathy of undetermined significance.
- Authors
Dizdar, Omer; Erman, Mustafa; Cankurtaran, Mustafa; Halil, Meltem; Ulger, Zekeriya; Yavuz, Burcu; Ariogul, Servet; Pınar, Aslı; Harputluoglu, Hakan; Kars, Ayse; Çelik, İsmail
- Abstract
The aim of this study was to investigate the prevalence of monoclonal gammopathy of undetermined significance (MGUS) in a geriatric population in Turkey and compare bone mineral densities and related laboratory parameters of MGUS patients with those who do not have MGUS. Among 1,012 patients enrolled, monoclonal band was detected in serum samples of 22 patients (2.17%), most of which were IgG type. Further tests revealed multiple myeloma and lung carcinoma in two patients. The remaining 20 patients were diagnosed with MGUS (1.97%). The clinical and laboratory parameters of patients with and without MGUS were mostly comparable; however, bone mineral density measurements of patients with MGUS were significantly lower than those without MGUS ( p = 0.007). We suggest evaluation of geriatric patients with MGUS for the presence of osteopenia/osteoporosis considering the high frequency observed in this study.
- Subjects
TURKEY; MONOCLONAL gammopathies; PLASMA cell diseases; BONE density; OSTEOPENIA; OSTEOPOROSIS; GERIATRICS
- Publication
Annals of Hematology, 2008, Vol 87, Issue 1, p57
- ISSN
0939-5555
- Publication type
Article
- DOI
10.1007/s00277-007-0376-5