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- Title
OC17.01: Effect of antihypertensive therapy on pre‐ and postnatal cardiovascular parameters in hypertensive disorders of pregnancy: a human and animal model.
- Authors
Palmrich, P.; Haase, N.; Sugulle, M.; Kalafat, E.; Haberl, C.; Schirwani‐Hartl, N.; Khalil, A.; Binder, J.
- Abstract
This article examines the effects of antihypertensive therapy on cardiovascular parameters in women with hypertensive disorders of pregnancy (HDP) and in a pre-eclamptic rat model. The study found that women with HDP experienced significant impairment of cardiac output, augmentation index, and systemic vascular resistance compared to healthy controls. Antihypertensive therapy improved cardiovascular parameters in women with gestational hypertension but did not have a significant impact on those with pre-eclampsia. The study suggests that current standard therapy for pre-eclampsia may not be sufficient to improve cardiovascular impairment.
- Subjects
LABORATORY rats; PREGNANCY in animals; VASCULAR resistance; CARDIAC output; BLOOD pressure
- Publication
Ultrasound in Obstetrics & Gynecology, 2024, Vol 64, p44
- ISSN
0960-7692
- Publication type
Article
- DOI
10.1002/uog.27837