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- Title
Preparation of a chiral hyperbranched polymer based on cinchona alkaloids and investigation of its catalytic activity in asymmetric reactions.
- Authors
ISLAM, Rafiqul; ULLAH, Mohammad Shahid; SALAM, Md. Abdus; ITSUNO, Shinichi
- Abstract
Cinchona alkaloid-derived sulfonamides and ester dimers containing chiral hyperbranched polymers have been successfully synthesized and applied as catalysts in asymmetric reactions. Several hyperbranched polymers derived from cinchona alkaloids, incorporating sulfonamides and esters, were synthesized through Mizoroki--Heck coupling polymerization. These polymers were subsequently applied in enantioselective Michael addition reactions. As the prepared polymers are not soluble in frequently used organic solvents, they act as efficient catalysts in the enantioselective reaction of β-ketoesters to nitroolefins, achieving up to 99% enantioselectivity with good yields. The insoluble property allows them to better satisfy "green chemistry" requirements and be used several times without losing the enantioselectivity.
- Subjects
MICHAEL reaction; SUSTAINABLE chemistry; CINCHONA alkaloids; ORGANIC solvents; CATALYTIC activity
- Publication
Turkish Journal of Chemistry, 2024, Vol 48, Issue 4, p512
- ISSN
1300-0527
- Publication type
Article
- DOI
10.55730/1300-0527.3677