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- Title
Prevalence of cardiac sarcoidosis in middle-aged adults diagnosed with high-grade atrioventricular block.
- Authors
Sasse, Alexander
- Abstract
This study in Israel investigated the prevalence and clinical characteristics of cardiac sarcoidosis in middle-aged patients with unexplained high-grade atrioventricular block. Thirty patients aged 18-65 years who presented with unexplained highgrade atrioventricular block and were referred for cardiac magnetic resonance imaging (MRI), positron emission tomography (PET)-computed tomography, or both, prior to pacemaker implantation were evaluated. 37% of patients had suspected cardiac sarcoidosis based on imaging findings; this was confirmed by tissue biopsy in 33% of patients. Compared with patients with idiopathic high-grade atrioventricular block, all cardiac sarcoidosis patients were male (100% vs 60%; p=0.029), were more likely to present with heart failure symptoms (50% vs 10%; p=0.047), had thicker interventricular septum on echocardiography (12.2 vs 9.45mm; p=0.002), and were more likely to present with right ventricular dysfunction (33% vs 10%; p=0.047).
- Subjects
NEW Zealand; SARCOIDOSIS diagnosis; SARCOIDOSIS; MAGNETIC resonance imaging; POSITRON emission tomography computed tomography; HEART block; DISEASE complications; MIDDLE age
- Publication
Cardiology Research Review, 2024, Issue 113, p3
- ISSN
1178-6086
- Publication type
Article