We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Pilot evaluation of a stellate ganglion block for the treatment of hot flashes.
- Authors
Pachman DR; Barton D; Carns PE; Novotny PJ; Wolf S; Linquist B; Kohli S; Smith DR; Loprinzi CL; Pachman, Deirdre R; Barton, Debra; Carns, Paul E; Novotny, Paul J; Wolf, Sherry; Linquist, Breanna; Kohli, Sadhna; Smith, DeAnne R; Loprinzi, Charles L
- Abstract
<bold>Purpose: </bold>Hot flashes are a significant problem in breast cancer patients, especially because the most effective therapy, estrogen, is often contraindicated. Based on recent pilot data from a single group supporting the use of a stellate ganglion block for the treatment of hot flashes, the present pilot trial was done to further evaluate the hypothesis that a stellate ganglion block may be a safe and effective therapy for hot flashes.<bold>Methods: </bold>In women with breast cancer who had hot flashes, a stellate ganglion block was performed after 1 week of baseline hot flash data collection. The main efficacy measures were the changes from baseline in hot flash frequency and hot flash score during the 6th week.<bold>Results: </bold>Ten patients were enrolled between 4/23/2009 and 7/10/2009; eight patients were evaluable. After the stellate ganglion block, the mean hot flash frequency and score decreased from baseline values by over 60% during some of the post-treatment weeks. The mean hot flash frequency and score at week 6 decreased from baseline values by 44% and 45%, respectively. There were no significant adverse events clearly attributed to the stellate ganglion blocks.<bold>Conclusions: </bold>The results of this pilot trial support that stellate ganglion blocks may be a helpful therapy for hot flashes. A prospective placebo-controlled clinical trial should be done to more definitively determine this contention.
- Publication
Supportive Care in Cancer, 2011, Vol 19, Issue 7, p941
- ISSN
0941-4355
- Publication type
journal article
- DOI
10.1007/s00520-010-0907-9