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- Title
Chemonucleolysis: the state of the art.
- Authors
Simmons, James W.; Nordby, Eugene J.; Hadjipavlou, Alexander G.; Simmons, J W; Nordby, E J; Hadjipavlou, A G
- Abstract
This review presents the history of chemonucleolysis, the techniques, indications, contraindications, and complications. Presenting an historical overview and comparison of success rates with surgical discectomy may provide a fresh understanding of the controversy surrounding chemonucleolysis and establish its efficacy in relation to more invasive treatments. A review of the literature from 1973 through 1998 for chemonucleolysis, open discectomy, and microdiscectomy provided published success rates for these procedures, and a mean rate with standard deviation was determined. In the experience and opinion of the authors, chemonucleolysis remains a viable alternative for patients who have exhausted all conservative means of treatment. Proper patient selection leads to success rates comparable to open discectomy and microdiscectomy.
- Subjects
CHEMONUCLEOLYSIS; DISCECTOMY; PATIENTS; INTERVERTEBRAL disk hernias -- Drug therapy; INTERVERTEBRAL disk surgery; MEDICAL records
- Publication
European Spine Journal, 2001, Vol 10, Issue 3, p192
- ISSN
0940-6719
- Publication type
journal article
- DOI
10.1007/s005860000234