Back to matchesWe found a matchYour institution may have access to this item. Find your institution then sign in to continue.TitleSynthesis and Biological Evaluation of 14-Alkoxymorphinans. Part 8. 14-methoxymetopon, an extremely potent opioid agonist.AuthorsSchmidhammer, Helmut; Schratz, Andrea; Mitterdorfer, JörgAbstract14-Methoxymetopon (= 5,14- O-dimethyloxymorphone; 4)and 14-ethoxymetopon ( 5) were synthesized from 14-hydroxy-5-methylcodeinone ( 6). In the AcOH-writhing test in mice, compound 4 was found to be ca. 20000 times more potent than morphine.PublicationHelvetica Chimica Acta, 1990, Vol 73, Issue 6, p1784ISSN0018-019XPublication typeArticleDOI10.1002/hlca.19900730623