The article focuses on the study of Zinc and vitamin C supplementation for SARS-CoV-2. Topics discussed include the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the etiological agent for the Coronavirus Disease 2019 and is the cause of a global health crisis; and examine whether high-dose zinc and/or high-dose ascorbic acid reduced the severity or duration of symptoms compared with usual care among ambulatory patients with SARS-CoV-2 infection.