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- Title
关节镜下清理术联合腓骨截骨术治疗膝关节骨性关节炎的疗效及对炎性因子的影响
- Authors
吴毅华; 罗高斌; 黄煜朗; 陈胜; 汪慧; 梁仁
- Abstract
Objective: To investigate the efficacy of arthroscopic debridement combined with fibular osteotomy in the treatment of knee osteoarthritis(KOA) and its effect on inflammatory factors. Methods: 99 patients with KOA who were admitted to Hechi Hospital Affiliated to Youjiang Medical University for Nationalities from March 2015 to December 2017 were selected, and they were divided into group A(n=46, arthroscopic debridement) and group B(n=53, arthroscopic debridement combined with fibular osteotomy)according to different surgical methods. The operation time, intraoperative bleeding volume and hospitalization time were compared between the two groups. The pain, knee function recovery and knee joint angle were compared between the two groups before operation,6 months after operation and 1 year after operation. The changes of inflammatory factors before operation and 1 month after operation were compared between the two groups. The incidence of postoperative complications was recorded in the two groups. Results: The operation time of group B was longer than that of group A(P <0.05). There was no significant difference in intraoperative bleeding volume and hospitalization time between the two groups(P>0.05). Visual analogue pain(VAS) score in group B was lower than that in group A at 6 months after operation and 1 year after operation, while Hospital special surgery(HSS), knee joint score and American knee society score(KSS) score were higher than those in group A(P<0.05). The levels of interleukin-6(IL-6) and tumor necrosis factor-α(TNF-α) were lower in the two groups at 1 month after operation than those before operation, and those in the group B were lower than those in the group A(P<0.05). The knee joint angle(F angle), femoral tibial angle(FT angle), tibiofemoral joint gap angle(JS angle) of group B were lower than those of before operation and group A at simultaneous time point(P<0.05). There was no significant difference in the incidence of complications between the two groups(P >0.05). Conclusion: Arthroscopic debridement combined with fibular osteotomy in the treatment of KOA has a definite effect. It can effectively relieve pain, improve knee function, reduce the levels of inflammatory factors, the surgical procedure is safe and can improve the lower limb force line of patients.
- Publication
Progress in Modern Biomedicine, 2019, Vol 19, Issue 10, p1966
- ISSN
1673-6273
- Publication type
Article
- DOI
10.13241/j.cnki.pmb.2019.10.035