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- Title
养血清脑颗粒对老年脑梗死后抑郁患者血清胱抑素C及认知功能的影响.
- Authors
王晓萍; 彭军; 姜丹; 黄丹; 刘孙琴
- Abstract
Objective: To investigate the effects of yangxue qingnao granule on the levels of serum cystatin C and cognition function in senile patients with depression after cerebral infarction. Methods: 74 patients with senile patients with depression after cerebral infarction who were treated in our hospital neurology department from June 2015 to June 2016 were selected, and randomly divided into control group and experiment group, with 37 cases in each group. The patients in the control group were treated with conventional drugs treatment, oral paroxetine hydrochloride, and the patients in the experiment group were treated with conventional drugs treatment combined with yangxue qingnao granule. 4 weeks were for a course of treatment, a total of a course of treatment. Results: After treatment, the clinical efficacy, serum C cystatin and cognitive function levels were compared between in the two groups. After treatment, compared with the control group, the clinical total effective rate of the experiment group was higher (P < 0.05), and the serum cystatin C level of the two groups were lower than before treatment after treatment (P < 0.05), the MMSE scored was higher than before treatment (P < 0.05); compared with control group, the serum cystatin C level of the experiment group was lower (P < 0.05), MMSE scored was higher (P < 0.05). Conclusions: Yangxue qingnao granule in the treatment of? patients with senile depression after cerebral infarction has remarkable clinical effect, and can significantly improve cognitive function, which may be relate to reduction of serum cystatin C level.
- Publication
Progress in Modern Biomedicine, 2017, Vol 17, Issue 8, p1477
- ISSN
1673-6273
- Publication type
Article
- DOI
10.13241/j.cnki.pmb.2017.08.018