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- Title
Prediction of fetal birthweight in Taiwanese women with pre-eclampsia and gestational hypertension using an equation based on maternal characteristics.
- Authors
Liu, Ching-Ming; Chang, Shuenn-Dyh; Cheng, Po-Jen
- Abstract
Aim: The purpose of the present study was to develop a method for predicting the birthweight of newborns in women with pre-eclampsia and gestational hypertension based on maternal characteristics and pregnancy-related factors. Methods: A total of 661 consecutive pregnant women with pre-eclampsia and gestational hypertension who delivered at Chang Gung Memorial Hospital from 1994 to 2003 were included in the analysis. Multivariate regression formulas (Models I and II) were derived from maternal characteristics to predict low infant birthweight. The sensitivity, specificity, positive predictive value, and negative predictive value were calculated and tested for these formulas. Results: The Model I formula was as follows: Using a cut-off value of 2210 g, the equation predicts the occurrence of a low birthweight baby with 90.9% sensitivity. If higher specificity is required, increasing the cut-off value to 2488 g yields a specificity of 95.2%. Receiver operating characteristic (ROC) curve analysis revealed an area under the curve of 93.7 (95% confidence interval [CI], 0.88 to 0.99) for low birthweight baby prediction in Model I. Conclusion: The results suggest that these regression formulas based on maternal characteristics may accurately predict low birthweight babies in pregnant women with pre-eclampsia and gestational hypertension. The cut-off values were determined and cross-validated by ROC curve analysis.
- Subjects
TAIWAN; BIRTH weight; PREECLAMPSIA; MOTHER-infant relationship; HYPERTENSION in pregnancy; MATERNAL health services
- Publication
Journal of Obstetrics & Gynaecology Research, 2008, Vol 34, Issue 4, p480
- ISSN
1341-8076
- Publication type
Article
- DOI
10.1111/j.1447-0756.2008.00813.x