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- Title
Balance Dysfunction in Parkinson’s Disease.
- Authors
Rinalduzzi, Steno; Trompetto, Carlo; Marinelli, Lucio; Alibardi, Alessia; Missori, Paolo; Fattapposta, Francesco; Pierelli, Francesco; Currà, Antonio
- Abstract
Stability and mobility in functional motor activities depend on a precise regulation of phasic and tonic muscular activity that is carried out automatically, without conscious awareness. The sensorimotor control of posture involves a complex integration of multisensory inputs that results in a final motor adjustment process. All or some of the components of this system may be dysfunctional in Parkinsonian patients, rendering postural instability one of the most disabling features of Parkinson’s disease (PD). Balance control is critical for moving safely in and adapting to the environment. PD induces a multilevel impairment of this function, therefore worsening the patients’ physical and psychosocial disability. In this review, we describe the complex ways in which PD impairs posture and balance, collecting and reviewing the available experimental evidence.
- Subjects
BRAIN physiology; PARKINSON'S disease diagnosis; NEURODEGENERATION; MUSCLE rigidity; DOPAMINE; DOPAMINE antagonists; POSTURAL balance; PARKINSON'S disease; SENSORIMOTOR integration; DISEASE complications; SYMPTOMS; DIAGNOSIS
- Publication
BioMed Research International, 2015, Vol 2015, p1
- ISSN
2314-6133
- Publication type
Article
- DOI
10.1155/2015/434683