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- Title
Valproic acid hypersensitivity and desensitization.
- Authors
Toker, Ori; Tal, Yuval; Horev, Liran; Shmoeli, Dorit; Gilboa, Tal
- Abstract
Rash, a hypersensitivity reaction, is a common cause of withdrawal from an effective antiepileptic drug (AED) in patients with epilepsy. We present a case of successful desensitization to valproic acid in a 12-year-old male with childhood absence epilepsy and a hypersensitivity reaction, whose epilepsy did not respond to other AEDs. Desensitization is a practical therapeutic solution for patients who develop a non-life-threatening hypersensitivity reaction to an AED for which there may be no substitute.
- Publication
Developmental Medicine & Child Neurology, 2015, Vol 57, Issue 11, p1076
- ISSN
0012-1622
- Publication type
journal article
- DOI
10.1111/dmcn.12835