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- Title
Potential Application of Marine Algae and Their Bioactive Metabolites in Brain Disease Treatment: Pharmacognosy and Pharmacology Insights for Therapeutic Advances.
- Authors
Khairinisa, Miski Aghnia; Latarissa, Irma Rahayu; Athaya, Nadiyah Salma; Charlie, Vandie; Musyaffa, Hanif Azhar; Prasedya, Eka Sunarwidhi; Puspitasari, Irma Melyani
- Abstract
Seaweeds, also known as edible marine algae, are an abundant source of phytosterols, carotenoids, and polysaccharides, among other bioactive substances. Studies conducted in the past few decades have demonstrated that substances derived from seaweed may be able to pass through the blood–brain barrier and act as neuroprotectants. According to preliminary clinical research, seaweed may also help prevent or lessen the symptoms of cerebrovascular illnesses by reducing mental fatigue, preventing endothelial damage to the vascular wall of brain vessels, and regulating internal pressure. They have the ability to control neurotransmitter levels, lessen neuroinflammation, lessen oxidative stress, and prevent the development of amyloid plaques. This review aims to understand the application potential of marine algae and their influence on brain development, highlighting the nutritional value of this "superfood" and providing current knowledge on the molecular mechanisms in the brain associated with their dietary introduction.
- Subjects
MARINE algae; THERAPEUTICS; BRAIN diseases; MARINE algae as food; PHARMACOGNOSY
- Publication
Brain Sciences (2076-3425), 2023, Vol 13, Issue 12, p1686
- ISSN
2076-3425
- Publication type
Article
- DOI
10.3390/brainsci13121686