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- Title
Long-term effect of exercise on improving fatty liver and cardiovascular risk factors in obese adults: A 1-year follow-up study.
- Authors
Zhang, Hui‐Jie; Pan, Ling‐Ling; Ma, Zhi‐Min; Chen, Zheng; Huang, Zhu‐Feng; Sun, Qian; Lu, Yan; Han, Cheng‐Kun; Lin, Ming‐Zhu; Li, Xue‐Jun; Yang, Shu‐Yu; Li, Xiao‐Ying
- Abstract
Exercise training can reduce hepatic fat accumulation and cardiovascular risk among patients with non-alcoholic fatty liver disease ( NAFLD), but how long these benefits extend beyond the period of active intervention is unclear. Intrahepatic triglyceride ( IHTG) content, measured by proton magnetic resonance spectroscopy, and metabolic risk factors among 220 obese people with NAFLD, who were randomly assigned to vigorous/moderate exercise, moderate exercise or no exercise (control), were assessed at 1 year after the 12-month exercise intervention. IHTG content was significantly reduced in the 2 exercise groups compared with the control group over the 12-month active intervention. It was significantly lower (by −2.39%) in the vigorous/moderate exercise group compared with the control group at the 1-year follow-up (95% confidence interval −4.72 to −0.05%; P = .045). Waist circumference and blood pressure remained significantly lower in the vigorous/moderate exercise group and the moderate exercise group compared with the control group at the 1-year follow-up. Visceral adipose fat remained significantly reduced, but with no differences among 3 groups. These findings suggest 12-month exercise intervention induced reductions in hepatic fat accumulation, abdominal obesity and blood pressure for up to 1 year after the active intervention, with some attenuation of the benefits.
- Subjects
EXERCISE &; psychology; FATTY liver; CARDIOVASCULAR diseases risk factors; OBESITY treatment; TRIGLYCERIDES
- Publication
Diabetes, Obesity & Metabolism, 2017, Vol 19, Issue 2, p284
- ISSN
1462-8902
- Publication type
Article
- DOI
10.1111/dom.12809