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- Title
Microtome Shaving Radiography: Demonstration of Loss of Mammographic Microcalcifications During Histologic Sectioning.
- Authors
Winston, Janet S.; Geradts, Joseph; Dong Feng Liu; Stomper, Paul C.
- Abstract
Mammographic-pathologic correlation of suspicious microcalcifications is essential for optimal diagnosis and local staging of early breast carcinoma. Loss of microcalcifications during histologic sectioning has been suggested as one reason for the occasional lack of microscopic visualization of microcalcifications in routinely processed breast biopsy specimens obtained for suspicious mammographic microcalcifications. Two case reports utilizing radiography of histologic shavings of stereotactic core biopsies and surgical excisional biopsies of mammographic microcalcifications provide concrete evidence of the loss of large calcific particles during the microtome process.
- Subjects
CANCER diagnosis; TUMOR classification; BREAST cancer; CALCIFICATION; RADIOLOGY; BIOPSY; MICROTOMES
- Publication
Breast Journal, 2004, Vol 10, Issue 3, p200
- ISSN
1075-122X
- Publication type
Article
- DOI
10.1111/j.1075-122X.2004.21300.x