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- Title
Neurological soft signs in obsessive compulsive disorder: standardised assessment and comparison with schizophrenia.
- Authors
Bolton, D.; Gibb, W.; Lees, A.; Raven, P.; Gray, J.A.; Chen, E.; Shafran, R.
- Abstract
While several studies have detected raised levels of neurological soft signs in patients with obsessive compulsive disorder (OCD), the specificity of these abnormalities remains uncertain. This study used a new standardised measure, the Cambridge Neurological Inventory (CNI), to assess soft signs in 51 subjects with OCD. Comparison was made with data on patients with schizophrenia and a non-clinical control group from a previously reported study. Individuals with OCD showed raised levels of soft signs compared with non-clinical controls in many categories of the CNI: Motor Coordination, Sensory Integration, Primitive Reflexes, Extrapyramidal Signs, and Failure of Suppression. Compared with patients with schizophrenia, the OCD group had lower levels of neurological signs in some CNI categories: Hard Signs, Motor Co-ordination, Tardive Dyskinesia, Catatonic Signs, and Extrapyramidal Signs. However, levels of soft signs in the OCD group did not significantly differ from those in the schizophrenia group in other CNI categories: Sensory Integration, Primitive Reflexes and Failure of Suppression. The significance of these patterns of findings is discussed.
- Subjects
OBSESSIVE-compulsive disorder; SCHIZOPHRENIA; NEUROLOGICAL disorders
- Publication
Behavioural Neurology, 1998, Vol 11, Issue 4, p197
- ISSN
0953-4180
- Publication type
Article