We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Postmastectomy Reconstruction Is Associated with Improved Survival in Patients with Invasive Breast Cancer: A Single-institution Study.
- Authors
BAKER, JENNIFER L.; MAILEY, BRIAN; TOKIN, CHRISTOPHER A.; BLAIR, SARAH L.; WALLACE, ANNE M.
- Abstract
Breast reconstruction after mastectomy positively affects psychosocial well-being; however, the influence of reconstruction on cancer outcomes is unknown. The objective of our study was to compare survival in reconstructed versus nonreconstructed patients after mastectomy. All consecutive female patients diagnosed with invasive breast cancer and treated with mastectomy between 2002 and 2011 were identified from our single-institution database. All cancer operations were performed by two surgeons. Survival was calculated using the Kaplan-Meier method and compared using the log-rank test. To identify the effect of reconstruction on survival, a multivariate Cox regression analysis was performed. Of 474 patients treated, 340 (71.7%) underwent breast reconstruction. At a mean follow-up 3.3 years, reconstructed patients had a longer 5-year survival (91 vs 74%, P < 0.001). After controlling for age, race, payer source, cancer stage, triple negative status, and receipt of radiation or chemotherapy, reconstructed patients maintained a survival advantage over nonreconstructed patients (hazard ratio, 0.47; 95% confidence interval, 0.25 to 0.88; P = 0.02). Patients with breast cancer who undergo reconstruction have longer survival than nonreconstructed patients. The explanation for this finding may be related to improved psychosocial qualities of life versus possible antitumorigenic effects of implants.
- Subjects
MAMMAPLASTY; MASTECTOMY; WELL-being; CANCER patients; RADIOTHERAPY; CANCER chemotherapy
- Publication
American Surgeon, 2013, Vol 79, Issue 10, p977
- ISSN
0003-1348
- Publication type
Article
- DOI
10.1177/000313481307901004