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- Title
Clinical features and burden of osteoporotic fractures among the elderly in the USA from 2016 to 2018.
- Authors
Lou, Yongfu; Wang, Wei; Wang, Chaoyu; Fu, Runhan; Shang, Shenghui; Kang, Yi; Zhang, Chi; Jian, Huan; Lv, Yigang; Hou, Mengfan; Chen, Lingxiao; Zhou, Hengxing; Feng, Shiqing
- Abstract
Summary: This study provides a national estimate of the incidence of hospitalizations and assesses the clinical features and outcomes during inpatient admission due to osteoporotic fractures diagnosed by ICD-10-CM/PCS among the elderly in the USA, using the US Nationwide Inpatient Sample, 2016–2018. Purpose: To provide a national estimate of the incidence of hospitalizations and assess the clinical features and outcomes during inpatient admission due to osteoporotic fractures (OFs) among the elderly in the USA. Methods: The study included all inpatients aged 65 years and older who participated in the US Nationwide Inpatient Sample (NIS). We conducted a retrospective analysis of hospitalizations with OFs diagnosed by the International Classification of Diseases, Tenth Revision, Clinical Modification/Procedure Coding System (ICD-10-CM/PCS), using the US NIS, 2016–2018. Trends in epidemiological characteristics and outcomes were calculated by annual percentage change (APC). Results: From 2016 to 2018, there were an estimated 0.16 million hospitalizations for OFs, and the estimated annual incidence rate changed from 995 cases per 1 million persons in 2016 to 1114 cases per 1 million persons in 2018 (APC, 5.8% [95% CI, 0.0 to 12.0]; P > 0.05). Over two-thirds of the patients (68.2%) were age-related osteoporosis with current pathological fracture, and OFs were more likely to occur in vertebra (51.7%) and femur (34.7%). During the hospitalization, the average length of stay (LOS) was 5.83 days, the average cost reached $60,901.04, and the overall mortality was 2.3%. All outcomes including LOS, average cost and mortality did not change significantly in 2016–2018 (all P values for trend were over 0.05). Conclusion: Between 2016 and 2018, the incidence rate of OFs remained relatively stable, but the total number of cases was huge. OFs was predominantly age-related, mostly in vertebrae and femurs, with relatively stable cost and mortality during hospitalization.
- Publication
Archives of Osteoporosis, 2022, Vol 17, Issue 1, p1
- ISSN
1862-3522
- Publication type
Article
- DOI
10.1007/s11657-022-01113-w