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- Title
Allergen Specific Immunoglobulin E Assay in Identification of Allergens in Allergic Diseases Patients.
- Authors
Ashari, Noor Suryani Mohd
- Abstract
Background: Several studies have been done to determine prevalence of allergen in patients with allergic diseases by using skin prick test and enzyme immunoassay. This study used allergen specific IgE assay (chemiluminescence technique) to determine the prevalence of allergens in allergic patients in HUSM. Methods: In this cross sectional study, patients with allergic rhinitis, atopic dermatitis and allergic asthma were included. Blood from 109 patients was analyzed for allergen specific IgE assay using chemiluminescence technique. Descriptive analysis was done for all 28 allergens to find out the prevalence of allergen. Results: In the aeroallergen group, the most common was D.farinae which account for 78.9% of allergic patients. Among the food allergen group, clam (56.0%) was the most commonly implicated food, and then followed by shrimp (52.3%). While for fungal allergen group, aspergillus was found to be the most common allergen (58.7%). Latex allergy account for 58% while animal fur of cat and dog account for 70.6% and 69.7%, respectively. For grass allergen, Bermuda and Johnson grass account for 54.1% and 56.9% respectively. Further analyses revealed that 96 (88.1%) patients were positive to at least one allergen tested while up to 77 patients (70.5%) were positive to two or more allergens. Conclusion: This study revealed that the most common allergen in allergic patients was from the aero allergen group (D. farinae). In addition, multiple sensitizations to allergens were common.
- Subjects
ALLERGENS; SKIN inflammation; ANTIGENS; ALLERGIC rhinitis; RESPIRATORY allergy; RHINITIS; ATOPY
- Publication
International Medical Journal, 2009, Vol 16, Issue 1, p25
- ISSN
1341-2051
- Publication type
Article