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- Title
Dupilumab reduces symptom burden in allergic rhinitis and suppresses allergen‐specific IgE production.
- Authors
Campion, Nicholas James; Doralt, Anna; Lupinek, Christian; Berger, Markus; Poglitsch, Katharina; Brugger, Jonas; Quint, Tamara; Gangl, Katharina; Sinz, Christoph; Bartosik, Tina; Liu, David Tianxiang; Landegger, Lukas David; Tu, Aldine; Stanek, Victoria; Berger, Uwe; Bangert, Christine; Schneider, Sven; Eckl‐Dorna, Julia
- Abstract
Dupilumab reduces symptom burden in allergic rhinitis and suppresses allergen-specific IgE production Keywords: allergen-specific; allergy; birch pollen; dupilumab; grass pollen EN allergen-specific allergy birch pollen dupilumab grass pollen 1687 1691 5 06/02/23 20230601 NES 230601 To the Editor, Type 2 immune responses underlie many respiratory diseases including allergy and chronic rhinosinusitis. In some patients, allergen-specific IgE levels in nMLF dropped even below the detection limit (e.g. patient #1, 2 and #3 for selected allergens). Male patients experienced on average a larger reduction in total IgE in nMLF but not in serum and the percentage reduction in serum IgE levels correlated negatively with the number of allergens a patient was sensitised to (Tables S2 and S3).
- Subjects
IMMUNOGLOBULIN E; ALLERGIC rhinitis; DUPILUMAB; ALLERGIC conjunctivitis; NASAL tumors; OLFACTOMETRY; SYMPTOM burden
- Publication
Allergy, 2023, Vol 78, Issue 6, p1687
- ISSN
0105-4538
- Publication type
Article
- DOI
10.1111/all.15653