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- Title
NFU1, Iron-Sulfur Biogenesis, and Pulmonary Arterial Hypertension: A (Metabolic) Shift in Our Thinking.
- Authors
Culley, Miranda K.; Perk, Dror; Chan, Stephen Y.
- Abstract
An editorial is presented on iron-sulfur biogenesis and pulmonary arterial hypertension. It mentions about enigmatic disease of the lung vasculature that is clinically defined by elevated mean pulmonary arterial pressure and pulmonary vascular resistance that results in significant and often fatal right ventricular (RV) failure; and link between metabolic reprogramming and progressive tissue dysfunction in the pulmonary vasculature.
- Subjects
IRON-sulfur compounds; ORIGIN of life; PULMONARY hypertension; LUNG diseases; PULMONARY blood vessels
- Publication
American Journal of Respiratory Cell & Molecular Biology, 2020, Vol 62, Issue 2, p136
- ISSN
1044-1549
- Publication type
Editorial
- DOI
10.1165/rcmb.2019-0309ED