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- Title
Increase in homocysteine levels after a half-marathon running: a detrimental metabolic effect of sport?
- Authors
Benedini, Stefano; Caimi, Alice; Alberti, Giampietro; Terruzzi, Ileana; Dellerma, Nicoletta; Torre, Antonio La; Luzi, Livio
- Abstract
Objective: The homocysteine level is considered an important cardiocerebral risk factor. Our aim was to investigate the impact of endurance training on the homocysteine cycle in élite and non-élite athletes. Methods: The level of physical activity was measured using a SenseWear armband in five healthy marathon runners. Two blood samples, the first under basal conditions and the second after running a half marathon, were obtained in all subjects by venepuncture. Biochemical parameters, including total homocysteine levels, were assessed. Results: Armband data indicated that each athlete ran the half marathon keeping a race pace close to their anaerobic threshold speed. Although the run times were very different between élite and non-élite athletes, a statistically significant increase in plasma homocysteine levels ( p=0.026) was observed in all runners. Conclusion: Endurance training for 75-100 min held at a race pace close to the anaerobic threshold speed induces an increase in serum plasma homocysteine level.
- Subjects
HOMOCYSTEINE; HALF marathons (Running); ENDURANCE sports; PHYSICAL activity; DIABETES
- Publication
Sport Sciences for Health, 2010, Vol 6, Issue 1, p35
- ISSN
1824-7490
- Publication type
Article
- DOI
10.1007/s11332-010-0094-6