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- Title
Immunophenotypic characterization of canine malignant lymphoma: a retrospective study of cases diagnosed in Poland Lower Silesia, over the period 2011-2013.
- Authors
Pawlak, A.; Rapak, A.; Drynda, A.; Poradowski, D.; Zbyryt, I.; Dzimira, S.; Suchański, J.; Obmińska‐Mrukowicz, B.
- Abstract
Lymphoma is the most frequently diagnosed cancer of the canine haematopoietic system. In this study, the flow cytometry and polymerase chain reaction ( PCR) analysis were used to characterize a series of canine lymphomas in detail. The aim of this study was to determine the incidence of B- and T-cell high-grade lymphomas and their immunophenotypic characterization in Lower Silesia, Poland. The results show that the frequency of each type of lymphoma is 71% for B-cell and 17% for T-cell lymphomas. In two cases the PCR techniques confirmed the presence of simultaneous double gene rearrangements of the BCR and TCR receptors.
- Subjects
SILESIA (Poland : Voivodeship); IMMUNOPHENOTYPING; LYMPHOMAS in dogs; DIAGNOSIS of dog diseases; FLOW cytometry; POLYMERASE chain reaction
- Publication
Veterinary & Comparative Oncology, 2016, Vol 14, p52
- ISSN
1476-5810
- Publication type
Article
- DOI
10.1111/vco.12112