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- Title
Study of rotating permanent magnetic field to treat steroid-induced osteonecrosis of femoral head.
- Authors
Xiaohua Pan; Deming Xiao; Xiaoyun Zhang; YuanShuai Huang; Bowen Lin
- Abstract
Abstract Sixty New Zealand rabbit models with steroid-induced necrosis of femoral head were exposed to a rotating permanent magnetic field (RPMF) (group A1–2 h/d for one month and group A2–2 h/d for two months), and the changes of femoral head, blood viscosity, serum cholesterol, triglyceride, and pressure within the hip joint cavity were measured and statistically analysed compared to that of control group (B1 and B2) and sham group (C1 and C2). After RPMF treatment, the osteogenesis regeneration of the necrotic femoral head was markedly improved, as was shown by micro-CT. Blood viscosity, serum cholesterol, triglyceride, and pressure in the hip joint cavity were found significantly reduced. RPMF could affect various critical aspects in the course of femoral head necrosis, which will be a promising measure in the prevention and treatment of steroid-induced necrosis of femoral head, especially in the early stage.
- Subjects
NEW Zealand; STEROID drugs; MAGNETOTHERAPY; TREATMENT of bone necrosis; FEMUR diseases; LABORATORY rabbits; BLOOD viscosity
- Publication
International Orthopaedics, 2009, Vol 33, Issue 3, p617
- ISSN
0341-2695
- Publication type
Article
- DOI
10.1007/s00264-007-0506-7