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- Title
New 18(4→3)-Abeo-Abietanoids from Tripterygium wilfordii.
- Authors
Ni, Lin; Zang, Ying-da; Yang, Jing-zhi; Li, Chuang-jun; Ma, Jie; Zhang, Dong-ming
- Abstract
Three 18(4→3)-abeo-abietanoids, a new natural product and two new compounds, named tripordolides A–C (1–3), were isolated from the leaves of Tripterygium wilfordii. Their structures were elucidated on the basis of their spectroscopic analysis, and the absolute configuration of compounds was confirmed by CD and X-ray crystallographic analysis using anomalous scattering of Cu Kα radiation. Compounds 1 and 3 showed moderate inhibitory activities against NO production in lipopolysaccharide-induced (LPS) RAW 264.7 macrophages in vitro.
- Subjects
NATURAL products; TRIPTERYGIUM wilfordii; LIPOPOLYSACCHARIDES; MACROPHAGES; SPECTRUM analysis; X-ray crystallography
- Publication
Molecules, 2018, Vol 23, Issue 10, p2467
- ISSN
1420-3049
- Publication type
Article
- DOI
10.3390/molecules23102467