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- Title
Lancifoliaine, a New Bisbenzylisoquinoline from the Bark of Litsea lancifolia.
- Authors
Sulaiman, Syazreen Nadia; Mukhtar, Mat Ropi; Hadi, A Hamid A.; Awang, Khalijah; Hazni, Hazrina; Zahari, Azeana; Litaudon, Marc; Zaima, Kazumasa; Morita, Hiroshi
- Abstract
A new bisbenzylisoquinoline, lancifoliaine (1), together with seven known alkaloids - N-allyllaurolitsine (2), reticuline (3), actinodaphnine, norboldine, pallidine, cassythicine and boldine - were isolated from the stem bark of Litsea lancifolia (Lauraceae). In addition to that of lancifoliaine, complete 13C-NMR data of N-allyllaurolitsine (2) was also reported. The alkaloidal structures were elucidated by means of high field 1D- and 2D-NMR IR, UV, and LCMS-IT-TOF spectral data. N-Allyllaurolitsine (2) showed a moderate vasorelaxant activity on isolated rat aorta.
- Subjects
ALKALOIDS; LAURACEAE; NUCLEAR magnetic resonance spectroscopy; INFRARED spectroscopy; LIQUID chromatography
- Publication
Molecules, 2011, Vol 16, Issue 4, p3119
- ISSN
1420-3049
- Publication type
Article
- DOI
10.3390/molecules16043119