We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Genome sequences of chikungunya virus isolates from an outbreak in southwest Bangkok in 2018.
- Authors
Chansaenroj, Jira; Wanlapakorn, Nasamon; Ngamsaithong, Chokchai; Thongmee, Thanunrat; Na nakorn, Natthaphon; Siriyasatien, Padet; Vongpunsawad, Sompong; Poovorawan, Yong
- Abstract
An outbreak of chikungunya virus (CHIKV) infection occurred in southwest Bangkok during the 2018 rainy season. The envelope glycoprotein E1 gene sequence of the infecting strain belonged to an East/Central/South African lineage with alanine at residue 226. Mutations in the predicted E1 (K211E) and E2 (V264A) proteins of CHIKV were identified in CHIKV-infected patients and in an Aedes aegypti mosquito. Analysis of the complete genome sequences showed marked differences from the strains causing previous outbreaks in Thailand in 2008-2009 and 2013 but showed similarities to strains from more recent CHIKV outbreaks in South and Southeast Asia.
- Subjects
BANGKOK (Thailand); SOUTHEAST Asia; THAILAND; NUCLEOTIDE sequencing; CHIKUNGUNYA virus; AEDES aegypti; ALANINE; MOSQUITOES; ALPHAVIRUS diseases
- Publication
Archives of Virology, 2020, Vol 165, Issue 2, p445
- ISSN
0304-8608
- Publication type
Article
- DOI
10.1007/s00705-019-04509-1