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- Title
First molecular characterization of canine parvovirus strains in Sardinia, Italy.
- Authors
Dei Giudici, S.; Cubeddu, T.; Giagu, A.; Sanna, G.; Rocca, S.; Oggiano, A.
- Abstract
Canine parvovirus type 2 (CPV-2) is responsible of acute hemorrhagic gastroenteritis in young dogs. CPV-2 emerged in 1978 in the USA, but new antigenic types, CPV-2a, 2b and 2c, have completely replaced the original type. In this study, we analyzed 81 animals collected in Sardinia, Italy. The VP2 sequence analysis of 27 positive samples showed that all antigenic CPV-2 types are circulating. CPV-2b seems to be the most widespread variant, followed by CPV-2a. Furthermore, 12 CPV-2b strains displayed further amino acid substitutions and formed a separate cluster in a phylogenetic tree, indicating regional genetic variation.
- Subjects
SARDINIA (Italy); MOLECULAR genetics; PARVOVIRUS diseases; DOG diseases; VIRAL gastroenteritis; SEQUENCE analysis; AMINO acid analysis
- Publication
Archives of Virology, 2017, Vol 162, Issue 11, p3481
- ISSN
0304-8608
- Publication type
Report
- DOI
10.1007/s00705-017-3457-3