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- Title
Pro-and Antioxidant Status in Newborn with COVID-19.
- Authors
Rychkova, L. V.; Darenskaya, M. A.; Petrova, A. G.; Semenova, N. V.; Moskaleva, E. V.; Kolesnikov, S. I.; Vanyarkina, A. S.; Kolesnikova, L. I.
- Abstract
There is practically no information on the state of oxidative stress reactions in newborns with coronavirus infections. At the same time, such studies are extremely important and can contribute to better understanding of the process of reactivity in patients of different ages. The content of pro- and antioxidant status indicators was assessed in 44 newborns with confirmed COVID-19. It was found that the content of compounds with unsaturated double bonds, primary, secondary, and final LPO products were elevated in newborns with COVID-19. These changes were accompanied by higher SOD activity and retinol level and reduced activity of glutathione peroxidase. Contrary to popular opinion, newborns can be a COVID-19-susceptible age group and require more close monitoring of metabolic reactions during the period of neonatal adaptation that is an aggravating background during infection.
- Subjects
OXIDANT status; NEWBORN infants; COVID-19; CORONAVIRUS diseases; GLUTATHIONE peroxidase; INFANTS; VITAMIN A; PREMATURE infants; RETINOL-binding proteins
- Publication
Bulletin of Experimental Biology & Medicine, 2023, Vol 174, Issue 4, p464
- ISSN
0007-4888
- Publication type
Article
- DOI
10.1007/s10517-023-05730-4