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- Title
Functional genomics: the modENCODE guide to the genome.
- Authors
Muers, Mary
- Abstract
The article focuses on the development of the model organism Encyclopedia of DNA Elements (modENCODE) Project to determine all sequence-based elements in the genomes. It mentions that the genome-wide data sets has gathered 237 Caenorhabditis elegans gnomes and 700 Drosophila melanogaster genomes which integrates RNA sequencing, DNA replication patterns and nucleosome occupancy. It also adds that the data-set integration disclosed network regulation to help improve forecasting of gene function.
- Subjects
NUCLEOTIDE sequence; GENES; DNA replication; CAENORHABDITIS elegans genetics; DROSOPHILA melanogaster genetics; GENOMES
- Publication
Nature Reviews Genetics, 2011, Vol 12, Issue 2, p80
- ISSN
1471-0056
- Publication type
journal article
- DOI
10.1038/nrg2942