We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Prognostic risk factors for failure of trabeculectomy with mitomycin C after vitrectomy.
- Authors
Inoue, Toshihiro; Inatani, Masaru; Takihara, Yuji; Awai-Kasaoka, Nanako; Ogata-Iwao, Minako; Tanihara, Hidenobu
- Abstract
Purpose: To evaluate the prognostic risk factors for failure of trabeculectomy with mitomycin C (MMC) in vitrectomized eyes. Methods: Retrospective cohort study. We reviewed the medical records of 116 patients (116 eyes) treated at Kumamoto University Hospital. The primary endpoints were persistent intraocular pressure of >21 mmHg, deterioration of visual acuity to no light perception, or additional glaucoma procedures. Multivariable analysis was performed with the Cox proportional hazards model. Results: The mean follow-up period was 36.5 months (range, 0.5-134.1 months). The probability of success 1 year after trabeculectomy was 55.1 %, 2 years after was 45.3 %, and 3 years after was 43.1 %. The multivariable model showed that higher preoperative intraocular pressure (IOP) [relative risk (RR), 1.05/mmHg; P = 0.0077] and neovascular glaucoma (NVG) (RR, 1.88; P = 0.049) were prognostic factors for surgical failure. Conclusions: The prognostic factors for surgical failure of trabeculectomy with MMC in vitrectomized eyes are a higher preoperative IOP and NVG.
- Subjects
OPHTHALMIC surgery; GLAUCOMA treatment; MITOMYCIN C; ANTINEOPLASTIC antibiotics; VITRECTOMY; VITREOUS body surgery
- Publication
Japanese Journal of Ophthalmology, 2012, Vol 56, Issue 5, p464
- ISSN
0021-5155
- Publication type
Article
- DOI
10.1007/s10384-012-0171-2