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Hsa-mir-145 is the top EWS-FLI1-repressed microRNA involved in a positive feedback loop in Ewing's sarcoma.
Published in:
Oncogene, 2011, v. 30, n. 18, p. 2173, doi. 10.1038/onc.2010.581
By:
- Ban, J;
- Jug, G;
- Mestdagh, P;
- Schwentner, R;
- Kauer, M;
- Aryee, D N T;
- Schaefer, K-L;
- Nakatani, F;
- Scotlandi, K;
- Reiter, M;
- Strunk, D;
- Speleman, F;
- Vandesompele, J;
- Kovar, H
Publication type:
Article
MYCN/c-MYC-induced microRNAs repress coding gene networks associated with poor outcome in MYCN/c-MYC-activated tumors.
Published in:
Oncogene, 2010, v. 29, n. 9, p. 1394, doi. 10.1038/onc.2009.429
By:
- Mestdagh, P.;
- Fredlund, E.;
- Pattyn, F.;
- Schulte, J. H.;
- Muth, D.;
- Vermeulen, J.;
- Kumps, C.;
- Schlierf, S.;
- De Preter, K.;
- Van Roy, N.;
- Noguera, R.;
- Laureys, G.;
- Schramm, A.;
- Eggert, A.;
- Westermann, F.;
- Speleman, F.;
- Vandesompele, J.
Publication type:
Article
Modulation of neuroblastoma disease pathogenesis by an extensive network of epigenetically regulated microRNAs.
Published in:
Oncogene, 2013, v. 32, n. 24, p. 2927, doi. 10.1038/onc.2012.311
By:
- Das, S;
- Bryan, K;
- Buckley, P G;
- Piskareva, O;
- Bray, I M;
- Foley, N;
- Ryan, J;
- Lynch, J;
- Creevey, L;
- Fay, J;
- Prenter, S;
- Koster, J;
- van Sluis, P;
- Versteeg, R;
- Eggert, A;
- Schulte, J H;
- Schramm, A;
- Mestdagh, P;
- Vandesompele, J;
- Speleman, F
Publication type:
Article
MYCN and ALKF1174L are sufficient to drive neuroblastoma development from neural crest progenitor cells.
Published in:
Oncogene, 2013, v. 32, n. 8, p. 1059, doi. 10.1038/onc.2012.106
By:
- Schulte, J H;
- Lindner, S;
- Bohrer, A;
- Maurer, J;
- De Preter, K;
- Lefever, S;
- Heukamp, L;
- Schulte, S;
- Molenaar, J;
- Versteeg, R;
- Thor, T;
- Künkele, A;
- Vandesompele, J;
- Speleman, F;
- Schorle, H;
- Eggert, A;
- Schramm, A
Publication type:
Article
DNA methylation silences miR-132 in prostate cancer.
Published in:
Oncogene, 2013, v. 32, n. 1, p. 127, doi. 10.1038/onc.2012.14
By:
- Formosa, A;
- Lena, A M;
- Markert, E K;
- Cortelli, S;
- Miano, R;
- Mauriello, A;
- Croce, N;
- Vandesompele, J;
- Mestdagh, P;
- Finazzi-Agrò, E;
- Levine, A J;
- Melino, G;
- Bernardini, S;
- Candi, E
Publication type:
Article
Oncogenic activation of FOXR1 by 11q23 intrachromosomal deletion-fusions in neuroblastoma.
Published in:
Oncogene, 2012, v. 31, n. 12, p. 1571, doi. 10.1038/onc.2011.344
By:
- Santo, E E;
- Ebus, M E;
- Koster, J;
- Schulte, J H;
- Lakeman, A;
- van Sluis, P;
- Vermeulen, J;
- Gisselsson, D;
- Øra, I;
- Lindner, S;
- Buckley, P G;
- Stallings, R L;
- Vandesompele, J;
- Eggert, A;
- Caron, H N;
- Versteeg, R;
- Molenaar, J J
Publication type:
Article
MicroRNA miR-885-5p targets CDK2 and MCM5, activates p53 and inhibits proliferation and survival.
Published in:
Cell Death & Differentiation, 2011, v. 18, n. 6, p. 974, doi. 10.1038/cdd.2010.164
By:
- Afanasyeva, E. A.;
- Mestdagh, P.;
- Kumps, C.;
- Vandesompele, J.;
- Ehemann, V.;
- Theissen, J.;
- Fischer, M.;
- Zapatka, M.;
- Brors, B.;
- Savelyeva, L.;
- Sagulenko, V.;
- Speleman, F.;
- Schwab, M.;
- Westermann, F.
Publication type:
Article
Monoallelic but not biallelic loss of Dicer1 promotes tumorigenesis in vivo.
Published in:
Cell Death & Differentiation, 2010, v. 17, n. 4, p. 633, doi. 10.1038/cdd.2009.202
By:
- Lambertz, I.;
- Nittner, D.;
- Mestdagh, P.;
- Denecker, G.;
- Vandesompele, J.;
- Dyer, M. A.;
- Marine, J.-C.
Publication type:
Article
Escape from p53-mediated tumor surveillance in neuroblastoma: switching off the p14<sup>ARF</sup>-MDM2-p53 axis.
Published in:
Cell Death & Differentiation, 2009, v. 16, n. 12, p. 1563, doi. 10.1038/cdd.2009.138
By:
- Van Maerken, T.;
- Vandesompele, J.;
- Rihani, A.;
- De Paepe, A.;
- Speleman, F.
Publication type:
Article
Comparative genomic hybridization (CGH) analysis of stage 4 neuroblastoma reveals high frequency of 11q deletion in tumors lacking MYCN amplification.
Published in:
International Journal of Cancer, 2001, v. 91, n. 5, p. 680, doi. 10.1002/1097-0215(200002)9999:9999<::AID-IJC1114>3.0.CO;2-R
By:
- Plantaz, D.;
- Vandesompele, J.;
- Van Roy, N.;
- Łastowska, M.;
- Bown, N.;
- Combaret, V.;
- Favrot, M.C.;
- Delattre, O.;
- Michon, J.;
- Bénard, J.;
- Hartmann, O.;
- Nicholson, J.C.;
- Ross, F.M.;
- Brinkschmidt, C.;
- Laureys, G.;
- Caron, H.;
- Matthay, K.K.;
- Feuerstein, B.G.;
- Speleman, F.
Publication type:
Article
Exon-level expression analyses identify MYCN and NTRK1 as major determinants of alternative exon usage and robustly predict primary neuroblastoma outcome.
Published in:
British Journal of Cancer, 2012, v. 107, n. 8, p. 1409, doi. 10.1038/bjc.2012.391
By:
- Schramm, A.;
- Schowe, B.;
- Fielitz, K.;
- Heilmann, M.;
- Martin, M.;
- Marschall, T.;
- Köster, J.;
- Vandesompele, J.;
- Vermeulen, J.;
- de Preter, K.;
- Koster, J.;
- Versteeg, R.;
- Noguera, R.;
- Speleman, F.;
- Rahmann, S.;
- Eggert, A.;
- Morik, K.;
- Schulte, J. H.
Publication type:
Article
MicroRNA-193b-3p acts as a tumor suppressor by targeting the MYB oncogene in T-cell acute lymphoblastic leukemia.
Published in:
Leukemia (08876924), 2015, v. 29, n. 4, p. 798, doi. 10.1038/leu.2014.276
By:
- Mets, E;
- Van der Meulen, J;
- Van Peer, G;
- Boice, M;
- Mestdagh, P;
- Van de Walle, I;
- Lammens, T;
- Goossens, S;
- De Moerloose, B;
- Benoit, Y;
- Van Roy, N;
- Clappier, E;
- Poppe, B;
- Vandesompele, J;
- Wendel, H-G;
- Taghon, T;
- Rondou, P;
- Soulier, J;
- Van Vlierberghe, P;
- Speleman, F
Publication type:
Article
Lysine-specific demethylase 1 restricts hematopoietic progenitor proliferation and is essential for terminal differentiation.
Published in:
Leukemia (08876924), 2012, v. 26, n. 9, p. 2039, doi. 10.1038/leu.2012.157
By:
- Sprüssel, A;
- Schulte, J H;
- Weber, S;
- Necke, M;
- Händschke, K;
- Thor, T;
- Pajtler, K W;
- Schramm, A;
- König, K;
- Diehl, L;
- Mestdagh, P;
- Vandesompele, J;
- Speleman, F;
- Jastrow, H;
- Heukamp, L C;
- Schüle, R;
- Dührsen, U;
- Buettner, R;
- Eggert, A;
- Göthert, J R
Publication type:
Article
A new recurrent inversion, inv(7)(p15q34), leads to transcriptional activation of HOXA10 and HOXA11 in a subset of T-cell acute lymphoblastic leukemias.
Published in:
Leukemia (08876924), 2005, v. 19, n. 3, p. 358, doi. 10.1038/sj.leu.2403657
By:
- Speleman, F.;
- Cauwelier, B.;
- Dastugue, N.;
- Cools, J.;
- Verhasselt, B.;
- Poppe, B.;
- van Roy, N.;
- Vandesompele, J.;
- Graux, C.;
- Uyttebroeck, A.;
- Boogaerts, M.;
- de Moerloose, B.;
- Benoit, Y.;
- Selleslag, D.;
- Billiet, J.;
- Robert, A.;
- Huguet, F.;
- vandenberghe, P.;
- de Paepe, A.;
- Marynen, P.
Publication type:
Article
Molecular analysis of 1p36 breakpoints in two Merkel cell carcinomas.
Published in:
Genes, Chromosomes & Cancer, 1998, v. 23, n. 1, p. 67, doi. 10.1002/(SICI)1098-2264(199809)23:1<67::AID-GCC10>3.0.CO;2-B
By:
- Van Gele, M.;
- Van Roy, N.;
- Ronan, S. G.;
- Messiaen, L.;
- Vandesompele, J.;
- Geerts, M. L.;
- Naeyaert, J. M.;
- Blennow, E.;
- Bar-Am, I.;
- Das Gupta, T. K.;
- van der Drift, P.;
- Versteeg, R.;
- Leonard, J. H.;
- Speleman, F.
Publication type:
Article
Genome wide measurement of DNA copy number changes in neuroblastoma: dissecting amplicons and mapping losses, gains and breakpoints.
Published in:
Cytogenetic & Genome Research, 2006, v. 115, n. 3/4, p. 273, doi. 10.1159/000095924
By:
- Michels, E.;
- Vandesompele, J.;
- Hoebeeck, J.;
- Menten, B.;
- de Preter, K.;
- Laureys, G.;
- van Roy, N.;
- Speleman, F.
Publication type:
Article
CADM1 is a strong neuroblastoma candidate gene that maps within a 3.72 Mb critical region of loss on 11q23.
Published in:
2008
By:
- Michels E;
- Hoebeeck J;
- De Preter K;
- Schramm A;
- Brichard B;
- De Paepe A;
- Eggert A;
- Laureys G;
- Vandesompele J;
- Speleman F;
- Michels, Evi;
- Hoebeeck, Jasmien;
- De Preter, Katleen;
- Schramm, Alexander;
- Brichard, Bénédicte;
- De Paepe, Anne;
- Eggert, Angelika;
- Laureys, Geneviève;
- Vandesompele, Jo;
- Speleman, Frank
Publication type:
journal article

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