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- Title
Dietary Advanced Glycation End Products Consumption as a Direct Modulator of Insulin Sensitivity in Overweight Humans: A Study Protocol for a Double-Blind, Randomized, Two Period Cross-Over Trial.
- Authors
de Courten, Barbora; de Courten, Maximilian P. J.; Schalkwijk, Casper G.; Walker, Karen Z.; Forbes, Josephine
- Abstract
Background: Advanced glycation end products (AGEs) are formed during the processing, storage, and cooking of foods. As part of a western diet, AGEs are consumed in excess and impair glucose metabolism in patients with type 2 diabetes. In the absence of diabetes, AGE-mediated decreases in insulin sensitivity and signaling have been postulated. However, randomized studies to test this relationship in humans are limited.
- Subjects
ADVANCED glycation end-products; GLUCOSE metabolism disorders; TYPE 2 diabetes; INSULIN resistance; GLUCOSE tolerance tests; INFLAMMATION; ANALYSIS of variance
- Publication
Journal of Medical Internet Research, 2015, Vol 17, Issue 7, p1
- ISSN
1439-4456
- Publication type
Article
- DOI
10.2196/resprot.4552