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- Title
Gastric Mixed Adenoneuroendocrine Carcinoma with a Trilineage Cell Differentiation: Case Report and Review of the Literature.
- Authors
Pericleous, Marinos; Toumpanakis, Christos; Lumgair, Heather; Caplin, Martyn E.; Morgan-Rowe, Luke; Clark, Ian; Luong, Tu Vinh
- Abstract
Most gastric neuroendocrine tumours are well differentiated and considered as neuroendocrine neoplasms, whilst poorly differentiated lesions are considered as neuroendocrine carcinomas and account for only 6-16% of gastric neuroendocrine tumours. Gastric mixed adenoneuroendocrine carcinomas are rare malignancies usually composed of a neuroendocrine carcinoma and an adenocarcinoma with a variable grade of differentiation. Here, we report an unusual and rare gastric mixed adenoneuroendocrine carcinoma with a trilineage cell differentiation including a neuroendocrine carcinoma, an adenocarcinoma and a squamous cell carcinoma. A brief discussion of the histopathological features, biological behaviour and treatment of this rare tumour type is presented. Copyright © 2012 S. Karger AG, Basel
- Publication
Case Reports in Oncology, 2012, Vol 5, Issue 2, p313
- ISSN
1662-6575
- Publication type
Article
- DOI
10.1159/000339611