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- Title
A Review on Inflammatory Bowel Diseases: Recent Molecular Pathophysiology Advances.
- Authors
Abdulla, Maheeba; Mohammed, Nafeesa
- Abstract
Inflammatory bowel diseases are considered immune disorders with a complex genetic architecture involving constantly changing endogenous and exogenous factors. The rapid evolution of genomic technologies and the emergence of newly discovered molecular actors are compelling the research community to reevaluate the knowledge and molecular processes. The human intestinal tract contains intestinal human microbiota consisting of commensal, pathogenic, and symbiotic strains leading to immune responses that can contribute and lead to both systemic and intestinal disorders including IBD. In this review, we attempted to highlight some updates of the new IBD features related to genomics, microbiota, new emerging therapies and some major established IBD risk factors.
- Subjects
INFLAMMATORY bowel diseases; PATHOLOGICAL physiology; HUMAN microbiota; IMMUNOLOGIC diseases; CROHN'S disease
- Publication
Biologics: Targets & Therapy, 2022, Vol 16, p129
- ISSN
1177-5475
- Publication type
Article
- DOI
10.2147/BTT.S380027