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- Title
Hydroxyapatite/β-tricalcium phosphate and enamel matrix derivative for treatment of proximal class II furcation defects: a randomized clinical trial.
- Authors
Peres, Maria F. S.; Ribeiro, Érica D. P.; Casarin, Renato C. V.; Ruiz, Karina G. S.; Junior, Francisco H. N.; Sallum, Enilson A.; Casati, Márcio Z.
- Abstract
Objective To clinically evaluate proximal furcations treated with hydroxyapatite/β-tricalcium phosphate ( HA/β- TCP) isolated or combined with enamel matrix derivative ( EMD). Material and Methods Thirty patients, presenting at least one proximal class II furcation defect, probing pocket depth ( PPD) ≥5 mm and bleeding on probing, were included. The defects were assigned to the HA/β- TCP group ( n = 15); open-flap debridement ( OFD) + HA/β- TCP filling, or, HA/β- TCP- EMD group ( n = 15); OFD + HA/β- TCP + EMD filling. Plaque ( PI) and gingival index ( GI), PPD, relative gingival margin position ( RGMP), vertical and horizontal attachment level ( RVAL and RHAL), vertical and horizontal bone level ( RVBL and RHBL), and furcation diagnosis were evaluated at baseline and at 6 months. Results Both groups presented improvements after therapies ( p < 0.05); however, no inter-group differences could be seen in any single parameter ( p > 0.05). At 6 months, the gains in rVCAL in the HA/β- TCP and HA/β- TCP- EMD groups were 1.47 ± 0.99 and 2.10 ± 0.87 mm, while the RHCAL gains were 1.47 ± 1.46 and 1.57 ± 1.58 mm ( p > 0.05). The RVBL and RHBL gains for the HA/β- TCP and HA/β- TCP- EMD group were 1.47 ± 1.13 and 1.70 ± 1.26 mm, and 1.90 ± 1.11 and 1.70 ± 1.37 mm respectively ( p > 0.05). The HA/β- TCP- EMD group showed seven closed furcations versus four in the HA/β- TCP group ( p > 0.05). Conclusion Both treatments lead to improvements in all clinical variables studied in the present trial. However, the closure of proximal class II furcation defects is still unpredictable.
- Subjects
BRAZIL; GUIDED tissue regeneration; PERIODONTAL disease treatment; DENTAL materials; ANALYSIS of variance; LONGITUDINAL method; RESEARCH funding; STATISTICS; T-test (Statistics); DATA analysis; EQUIPMENT &; supplies; RANDOMIZED controlled trials; BLIND experiment; SEVERITY of illness index; DATA analysis software; THERAPEUTICS
- Publication
Journal of Clinical Periodontology, 2013, Vol 40, Issue 3, p252
- ISSN
0303-6979
- Publication type
Article
- DOI
10.1111/jcpe.12054