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- Title
Analysis of rapid eye movement periodicity in narcoleptics based on maximum entropy method.
- Authors
Honma, Hiroshi; Ohtomo, Norio; Kohsaka, Masako; Fukuda, Noriko; Kobayashi, Riko; Sakakibara, Satoshi; Nakamura, Fumihiro; Koyama, Tsukasa
- Abstract
We examined REM sleep periodicity in typical narcoleptics and patients who had shown signs of a narcoleptic tetrad without HLA-DRB1*1501/DQB1*0602 or DR2 antigens, using spectral analysis based on the maximum entropy method. The REM sleep period of typical narcoleptics showed two peaks, one at 70–90 min and one at 110–130 min at night, and a single peak at around 70–90 min during the daytime. The nocturnal REM sleep period of typical narcoleptics may be composed of several different periods, one of which corresponds to that of their daytime REM sleep.
- Subjects
RAPID eye movement sleep; NARCOLEPSY; THERAPEUTICS
- Publication
Psychiatry & Clinical Neurosciences, 1999, Vol 53, Issue 2, p203
- ISSN
1323-1316
- Publication type
Article
- DOI
10.1046/j.1440-1819.1999.00488.x